I purchased vitex after I was diagnosed with polyps on my ovaries. My Dr. said it was due to low progesterone levels. My husband and I only found out due to the fact we were having a hard time conceiving, which was unusual, we already have four kids. After about a year of nothing I purchased this as a last ditch effort. I only took half the bottle and was pregnant the first time we tried again. They are great, with no side effects. Highly recommend to anyone!