You Can Reduce Excess Estrogen with Supplement DIM

You Can Reduce Excess Estrogen with Supplement DIM

CB060669Many fertility issues are the result of having estrogen dominance in the body. There are many ways for the body to become estrogen dominant, including:

  • The environment
  • Eating non-organic meat
  • Stress
  • Processed soy foods
  • Chemicals in products

The good news is that there is now a natural way to rid the body of an overabundance of estrogen: a supplement called DIM.

What is DIM?

Scientist knew there were powerful nutrients in crucifers like broccoli, cauliflower, kale and rutabaga, but until they began to isolate the various phytonutrients, they didn’t realize just how important they were. One of the plant nutrients discovered was DIM, which stands for diindolylmethane. It comes from the plant chemical I3C short for indole-3-carbinol.

To get just 10-30 mg of DIM you would have to eat one-and-a-half pounds of cruciferous vegetables!

Diindolylmethane releases in the stomach after you chew and swallow the vegetables. It balances the hormones and aids in the breakdown of estrogen. Estrogen dominance is a major cause of the fertility issues women face today. Endometriosis, PCOS, and Ovarian Cysts, are all estrogen dominant conditions.

DIM also helps men. Both men and women’s bodies can experience estrogen dominance. Men’s estrogen increases with age and is subject to the same estrogen balance problems a female body may face, including improper metabolism of estrogen.

Women having troubles becoming pregnant may benefit from the hormone balancing actions of DIM.

Signs of Estrogen Dominance:

  • PMS
  • Cramps
  • Fibroids
  • Endometriosis
  • Heavy menstrual bleeding
  • Ovarian cysts
  • Recurrent miscarriage
  • PCOS
  • Lack of ovulation

What is Estrogen Dominance?

Estrogen and progesterone work in unison for the body’s benefit. As people age, their hormone levels reduce, particularly for women during the perimenopause stage and beyond. The levels of progesterone decrease faster than estrogen. This decrease may creates an imbalance in hormone levels.

Younger women can also suffer from hormone imbalance. During a normal menstrual cycle, when the egg releases at ovulation, the empty follicle changes to the corpus luteum, which is the place that produces progesterone. If something goes wrong, it may not produce enough progesterone. When you consider that progesterone is necessary for womb maintenance, you will realize the potential harm that a reduction in progesterone might have on the developing fetus or fertility.

Many factors contribute to the development of estrogen dominance. Obesity is one of the factors. The ovaries produce androstenedione, which is a male hormone. Fat cells change those hormones to estrogen. Pesticides, estrogen in animal food supplies, stress and high intake of caffeine also are factors attributed to estrogen dominance.

Studies now link infertility to estrogen dominance by disrupting the process of ovulation and in some cases lowering a man’s sperm count or causing poor sperm health. Estrogen dominance plays a key role in the development and proliferation of endometriosis, uterine fibroids and ovarian cysts, which are all issues that can dramatically affect fertility.

Do You Have Estrogen Dominance?

Symptoms of estrogen dominance:

Allergy symptoms like asthma and hives
Thyroid issues
Breast cancer
Breast tenderness
Decreased sex drive
Depression with agitation and/or anxiety
Dry eyes
Early onset of menstruation
Fat gain, usually around the middles
Fatigue
Foggy thinking
Hair loss
Headaches
Increased blood clotting
Fertility issues
Irregular periods
Insomnia
PMS
Polycystic ovaries
Sluggish metabolism

How to Use DIM to Reduce Excess Estrogen

DIM is found in vegetables like broccoli, Brussels sprouts and cauliflower, but in order to get just 10-30 mg of DIM you would have to eat one-and-a-half pounds of these cruciferous vegetables! While that amount is better than none, it is not the therapeutic dosage. Most experts recommend taking 100 to 200 mg of DIM a day.

Click here to purchase a product with these ingredients…

References:
– Auborn, K. J., Fan, S., Rosen, E. M., Goodwin, L., Chandraskaren, A., Williams, D. E., … & Carter, T. H. (2003). Indole-3-carbinol is a negative regulator of estrogen. The Journal of nutrition, 133(7), 2470S-2475S.
– ZELIGS, M. A. (1998). Diet and estrogen status: the cruciferous connection. Journal of Medicinal Food, 1(2), 67-82.
– McDougal, A., Gupta, M. S., Morrow, D., Ramamoorthy, K., Lee, J. E., & Safe, S. H. (2001). Methyl‐substituted diindolylmethanes as inhibitors of estrogen‐induced growth of T47D cells and mammary tumors in rats. Breast cancer research and treatment, 66(2), 147-157.
4. Eleutério Junior, J., Cavalcante, D. I. M., Ferreira, F. V. D. A., & Medeiros, F. D. C. (2001). Estrogen and progesterone receptors in peritoneal fluid cell sediment in pelvic endometriosis: immunocytochemical study. Revista Brasileira de Ginecologia e Obstetrícia, 23(2), 83-86.

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[-] 70 Comments
  1. I have been taking DIM for one month, my question now is do I still take it when I get my period, or do I stop like the Progesterone cream? Thanks so much:)

  2. Hello I am 19 years old and I am thinking about taking DIM – I’m quite certain that I have high estrogen, however, I haven’t had a period for quite some time now and wonder if that’s a sign of estrogen dominance or not. Also, I’m wondering that if I take it I will end up with a surprise period..?

    Thank you for all the help!

  3. I am 45 years old and learned I had estrogen dominance through a saliva panel. Also with extremely high DHEA and the testosterone level of a 20 year old. I took DIM for 30 days but stopped when I was 2 weeks late. My periods have always been like clockwork. For 2 weeks I felt horrible until I finally started. Did I just not take the DIM long enough to see a difference?

    • Hi Dreanna,

      To be honest there really is no way for me to know what may be going on here. DIM not only helps the body to metabolize estrogen, but testosterone as well, so it may be that your body is adjusting to the action of DIM. If you are not trying to conceive, but just wanting to support your hormonal health overall, I would say you could continue on to see how your body responds this next cycle. If you are trying to conceive, missing cycles is not good and if you suspect it could be linked to DIM, you may want to discontinue it, or significantly lower dose. I am not sure how you are taking it or how much, but one (100mg) capsule a day would be lowest dose. Also, not sure what brand you are taking… that may make a difference.

  4. Hi there, I am 24 and I have PCOS. My husband and I have been TTC for 4 years now with no luck. We tried clomid, HCG, and IUI. Then switched to a more natural approach and tried using Black Cohosh to stimulate ovulation. I got positive OPKs but never my BFP. I have recently discovered that PCOS is caused by estrogen dominance. If I were to take DIM in combination with Black Cohosh (considering I got a positive OPK) would that defeat the purpose of taking DIM?
    I am also using Progessence Plus Essential Oil and Fertilaid.

    Thank you, your response is greatly appreciated.

    • Hi Jennifer,

      DIM helps the body to utilize and process estrogen more efficiently, so it shouldn’t interfere with Black Cohosh. I hope that makes sense. It isn’t removing all your estrogen, it helping the body manage estrogen.

  5. I’m 25 yrs old woman and I started taking DIM 3 days ago. I would like to know how long can i take it before taking a break from it? Thanks

    • Dear Genevieve,

      In general, we suggest sticking with a natural fertility programs, or herbs and nutritional supplements (like DIM) for at least three months time. Many take them longer. Listen to your body! If you begin to experience balance and the changes you hope for, at that point weaning off of DIM could be considered. That said, DIM can be taken long term.

  6. hello! i am a 21 year old woman … i didnt know what estrogen dominance was until i came across it on FB and reading the symptoms i realized i had many of those .. two big ones that has me concerned was the anxiety(i see a therapist already) and infertility.. ive been with my boyfriend for 1and a 1/2 years and have not once used any type of contraceptive and i have not gotten pregnant.. also i have the sluggish metabolism, headaches which were very rare for me , cramps and recently late periods which i used to be exact, theres been 5-6 times ive gotten allergy reactions to god knows what (they look like mosquito bites) and lots of fatige! so exactly what tests should i get done?? thank you

    • Hi ailin,

      It sounds like you should see your doctor and request a full hormone panel, including thyroid hormones.
      Progesterone
      Estradiol
      FSH
      LH
      Prolactin
      Testosterone
      Sex hormone binding globulin
      24 hr. urinary free cortisol
      Glucose Tolerance Test
      Thyroid Panel
      Blood Lipid Profile

      I hope that helps!

  7. In what way are thyroid issues considered an allergen, similar to asthma or hives? (referenced above in the list under Do You Have Estrogen Dominance?)

    • Dear Joanna,

      Thyroid issues are not considered an allergy symptom similar to asthma or hives. I think in list above that thyroid issues should be another bullet point. 😉 Thank you for asking and catching an edit we need to make. Great editing eye!

  8. I have endometriosis due to which I suffer from blocked fallopian tubes, endometrioma on my ovaries and suspected Adenomyosis. But my blood work shows normal hormones and normal estrogen levels. Do you think DIM will be helpful for me, even with normal blood estrogen levels?
    And can I use this throughout my cycle or should I stop using it after ovulation?
    Can I combine this with progesterone cream?

    • Dear Sarah,

      DIM Complete may be useful, however if your estrogen and progesterone levels showed normal after testing, it may be best to look into the other causes of endometriosis. If you choose to try Fertilica DIM Complete, general suggested use is that is be taken all cycle long without taking a break and discontinued upon first determination of pregnancy. Fertilica DIM Complete can be combined with Fertilica Natural Progesterone Cream.

      We also share information about important natural alternative therapies and the most up-to-date medical procedures for endometriosis in our guide to The Best Natural Alternative Therapies for Endometriosis.

      Take care!

  9. I am 46 years old. I had two episodes of prolong bleeding for the last two years.I like to know if I can take DIM and Menstrual Reg(Nature’s Sushine) Herbal supplement together or I just need DIM. I have excess uterine tissue growth during my menstruation flow and prolong bleeding. I developed anemia and had blood transfusion this last cycle. I am being schedule to have an IUD to help with bleeding. I want to rely on herbal supplements to help regulate my cycles but I don’t know if it is wise to also have an IUD implantation. I also have a 5m cyst. I didn’t get tested for estrogen and progesterone levels. I was tested for cancer cells in my uterus and cervix, results were negative.

    • Hi Betty,

      DIM is fine to combine with the herbs in that formula. Be sure you are keeping your iron intake up, by eating iron rich foods and considering a whole food iron supplement like Blood Builder or Floradix Iron and Herbs. Do you think you are in perimenopause? If so, the help with the transition, you may want to learn more about the herb Vitex agnus-castus. Based on the herbal profile of the Menstrual Reg. product, it seems like a drying formula, which may not be indicated for use by you long-term, since you said this has only happened to you twice. You may want to consider something for hormonal balance and longer-term menstrual cycle support, of which Vitex applies.

      I hope this helps!

  10. Hi, I am 52 years old and have prothombin 20210 mutation which means I am at risk of my blood clotting easily. Could DIM help with my menopause systems which include night sweats and insomnia without affecting my blood further?

    • Hi Janelle,

      To the best of my knowledge, DIM doesn’t affect blood clotting issues. I also am not sure that DIM is the best choice for the menopause symptoms you are experiencing. While they are associated with hormonal changes taking place in menopause, I am not confident DIM is the best natural supplement for those issues. Because we specialize in working with women in their reproductive years, I think you may be better served from the team over at WomentoWomen.com

      As always, it is best to speak with your doctor about beginning any new nutritional supplements, especially if you are concerned about your health history in regard to supplementation.

      All the best!

  11. I had my Mirena IUD removed in late December. I had bleeding and clotting for 30 days until they finally did a d&c. During the 30 days I was on 3 different types of meds to control the bleeding. The d&c was 5 days ago and things seem to be going well. I am trying to rebalance my hormones and get rid of the 5cm ovarian cyst they found during this whole process. I am planning on taking DIM, Wild Yam and Vitex, along with caster oil compress to remove toxins. Are those things safe to take together? Do you have any other suggestions? I appreciate your help!

    To clarify. It was December 2015. I was on provera, gildess, and finally norethin before surgery.

  12. Hi,
    I’m 41 and TTC #2. For the last year my LP has shortened to 10 days and I have 3-4 days of spotting before my period starting on 7 days past ovulation. I’ve been tested 3 times for 7dpo progesterone levels and they all come back “normal” even though I’m spotting at the time. With doing research and really looking at my symptoms (cold feet and hands, generally cold, heightened depression/anxiety,clotty periods, etc.), I’m starting to think I’m estrogen dominant. Would I take DIM all cycle long, or just in the LP? Also, will taking DIM disrupt anything with ovulation? I just know in the follicular phase estrogen is naturally high I just don’t want to mess up my cycle any more than it is.

    • Dear Karen,

      Fertilica DIM Complete is suggested all cycle long without taking a break. It helps the body metabolize excess, unneeded estrogen that we get thru diet and lifestyle. It is not known to impact healthy, needed estrogen.

      Spotting can be caused by a number of events from disturbance in hormone balance, failure to ovulate, fertility health issues, excessive exercise and poor nutrition to name a few.

      It may also be worth talking to your doctor about testing thyroid function. I am not a medical doctor, but the symptoms you shared can be associated with low thyroid function as well.

      There are simple ways known to reverse luteal phase defect worth learning more about as well.

      I hope this is all helpful!

  13. Hi there,

    I always had an irregular periods, but now that I’m trying to conceive – I would like to have a healthier reproductive system. Would the mix of DIM and Vitex aid with ovulation and regulating periods? I have been DIM for the last few months but it didn’t help much with regulating.

    • Greetings!

      DIM Complete and Fertilica Vitex can be taken together to support the body in achieving hormonal balance to have a healthy menstrual cycle and properly metabolize excess estrogen. Beyond this, I am not sure I can guide you further without knowing more about you and your lifestyle, so consider referring to our Natural Guide for Menstrual Health for additional tips.

      If you are still unsure of how to proceed, please consider working one on one with our fertility herbalist who can lay out an entire natural fertility program for you based on your specific fertility health needs through a Fertility Consultation.

  14. Dear..,

    Can DIM supplements be combined with oral contraceptives? Will the reliability of the pill be reduced by the effects on estrogen of DIM?

    I hope to hear from you!
    Kind regards, Lisette de Jong

    • Dear Lisette,

      The use of DIM with oral contraceptives is not suggested. If interested in doing so, it would be best to talk to your healthcare provider about combining them.

      Take care!

  15. Hi! I wanted to know if DIM can be taken safely while actively trying to conceive? I am planning to take this with Vitex. Thanks!

  16. I had left sided salpingectomy due to ruptured ectopic pregnancy. Now I want to conceive, but I have low progesterone levels. After progesterone and oradexon therapy for 4 month I didn’t get pregnant. My doctor suggests IVF for me. What should I do?

    • Dear Jahan,

      I am sorry you went through this!

      A helpful place to start may be our Progesterone Fertility Guide. There you will read about the female fertility herb Vitex and about natural progesterone cream, each known to support healthy progesterone levels.

      Vitex encourages luteinizing hormone (LH) production while mildly inhibiting the release of follicle stimulating hormone (FSH). This indirectly boosts progesterone production. Progesterone cream is a bioidentical hormone cream that can help to supplement the body’s own progesterone levels.

      Then, know that with one functioning, healthy fallopian tube, conception may happen the months that ovulation occurs from the ovary on the side of that tube. Ovulation happens from one ovary one cycle and the other the next – the event alternates from side to side. Knowing this, it is also going to be helpful to learn the tools available to help you detect ovulation (if you do not already do this).

      I hope this is all helpful!

  17. I am almost 52 years old, and I am almost positive that I am estrogen dominant. I have extremely achy joints in the morning where I can’t move very quickly. I also have a tire around my waist that I can’t get rid of through exercise and healthy eating. I eat no sugar, dairy or wheat. I eat lots of vegetables and healthy protein. I am beginning to take DIM in hopes that it will help. Is it okay for me to continue eating broccoli, cauliflower, and brussel sprouts daily along with the DIM (100 mgs daily)? Do you think I’ll notice a difference in my achy joints as well?

    • Dear Cynthia,

      Whole food sources of DIM can be consumed with a DIM supplement. I am not certain if taking DIM will offer relief from achy joints.

  18. Where do you buy DIM?

  19. Tired of ballooning on the scale and working out like crazy with no success. PCOS is no joke, however, I came across an article on DIM and very hopeful this will balance out my hormones. I will keep everyone posted. This website is very informative. Thank you!

  20. Should you double the dosage to lose bloating from perimenopause?

    • Dear Susan,

      It is always best to follow suggested use guidelines. Exceeding this dose is not advised unless being advised to do so by a qualified practitioner. Taking more than suggested does not mean the supplement will be more effective.

  21. I have high estrogen, low progesterone, low testosterone. I just started taking DIM about 5 days ago. I also had switched my Chasteberry brand because the one I had been taking also had black cohosh in it and heard that raises estrogen. So, I switched brands about the time I started taking DIM. Now, I have broken out in hives. I’m normally not allergic to anything and have never experienced this before. Are there brands of either you recommend? Is it possible that the mixture of both caused the hives or the brand of either? I didn’t take either today because I look terrible and am itching like crazy. I’m hoping this will go away in another day or so, but would like to find new supplements.

    • Dear Leslie,

      I am so sorry this has been your experience. I have never heard of the brands of DIM that have been sold in the Natural Fertility Shop, Source Naturals and Olympia Labs, combined with Chaste tree berry, Vitex, causing hives. Might there be a filler or other ingredient that could be the culprit?

      Fertilica brand is the brand sold by the Natural Fertility Shop that we support using. There are Vitex supplements in the Fertilica brand and at the end of this month there will also be a DIM supplement. Watch for that soon!

      I too hope the symptoms subside soon!

  22. Can DIM be taken with Chaste Tree?

  23. Can DIM be taken together with Royal Jelly and Propolis? Many thanks

  24. Does DIM provide folic acid?

  25. Hi!

    I love your website! I’m learning new things every day. Maybe you can help me pinpoint if I’m estrogen dominant, I think I am, but I have so many different symptoms that I’m never 100% sure what the problem is. I have very painful ovulation, an excruciating pulling pain on one side of my body that starts a few days before in my back and upper thighs. But I also have about 3 days of spotting before my period (and about 3 days after as well) very heavy bleeding with a lot of large clots and extremely bad period cramps. My cycle is long, about 35 days, and I have quite bad PMS for a week or more, waiting for it to actually start. Would Maca and DIM help me?

    • Dear Milla,

      Thank you for your kind words. I am thankful the information we share has been helpful.

      I am sorry you are experiencing these issues!

      Our Estrogen Fertility Guide shares in great detail about estrogen and estrogen dominance. There is even a checklist to help one determine if estrogen dominance may be a issue. The guide also shared natural ways to support the body in managing excess estrogen and achieving hormone balance.

      I hope this is helpful!

  26. I have had hormonal acne all my life and at age 30 it is as severe as ever. I started taking DIM about two years ago and my acne cleared completely within one week. It stayed gone until I stopped taking DIM since my husband and I began trying to conceive and I wasn’t sure how it would affect conception. After stopping DIM, my acne came back within 4 days as bad as ever. Blood tests have revealed that my testosterone levels are elevated but my estrogen levels are on the low end of normal range. I’m curious if DIM is good for me given that I don’t have high estrogen… it certainly was a miracle for my skin!

  27. Hello, is it ok to take DIM only in the second phase (from what day and how long?) Thanks

    • Dear Maryana,

      Most experts recommend taking 100 to 200 mg of DIM each day of the menstrual cycle with meals. DIM can be taken in preparation for conception and when trying to conceive. I do not know of a reason to avoid it during the follicular phase of the menstrual cycle.

      Upon first determination of pregnancy, DIM is to be discontinued.

  28. Thank you so much for all the info.
    I have been taking DIM for a little more than a month now and I am experiencing very dry eyes and hip pains (same hip pains I usually only get during pregnancy). Could DIM be lowering my estrogen too much? I am taking it hoping it will balance my hormones and will help me stay pregnant as I keep getting pregnant and loosing the pregnancy right away (between 4 and 5 weeks). 6 pregnancies lost and after about a million tests, nothing is wrong on paper. Although I know something is not right (really bad night sweats several days before periods, late ovulation, mood swings…).

    • Hello Sofia!

      I am very sorry for your losses and what you are going through.

      DIM supports the body in metabolising excess bad estrogens, not your good estrogen. DIM is not going to strip away all of your estrogen, but remove bad estrogens from your body to promote healthy good estrogen metabolism function in the body.

      Have you begun or are you taking anything else? Might you be pregnant again?

      Consider the 5 Steps To Decreasing the Chance of Recurrent Miscarriages as you continue to educate yourself.

      You may also want to consider a Natural Fertility Consultation. Our email consultations provide you with a personalized written guide and audio recording from our fertility herbalist explaining the best natural therapies, herbs and nutritional supplements for your unique fertility issues.

      Best wishes to you!

  29. Thank you so much for a wonderful website! For few years I have been having heavy long periods, doctor said it is because I have a fibroid. I am trying to conceive for 2 years with no success. Also, for last 3 months I had no ovulation.I think I have estrogen dominance.So I bought DIM and for 4 weeks taking 4 tablets of DIM (double dose), also Donq Quai (not during period), primrose oil, black cohosh, enzymes and vitamins. My last period started 3 days late and still on for 10 days, just spotting now.Got some pimples on my face and chest, what I usually don’t get. Ordered also progesterone cream from your website, waiting to arrive. Is starting DIM can affect the time and length of period?

    • Dear Lolita,

      DIM is supportive of helping the body metabolize excess “bad” estrogen. There could be potential for the cycle to shift as a result of the body ridding itself of excess estrogen and utilizing its natural estrogens or the herbs you are also taking. These shifts should work themselves out within 1-3 cycles of use.

  30. My estrogen is high and progesterone low, both just within range so Dr wont do anything yet about not conceiving. I’m not sure which is the initial issue: estrogen dominance or progesterone deficient. Would it make sense to take DIM as well as Vitex or just one?

    • Elizabeth Willett, MA, CH

      Dear Jenn,

      Diet, lifestyle, exercise and even stress all have been found to impact hormone balance. DIM is supportive of helping the body metabolize excess “bad” estrogen and Fertilica Vitex may in part be supportive of the body’s natural progesterone levels. They can be taken together.

      Consider also learning more about dietary and lifestyle ways to support hormone balance that I mentioned in the article, Restore Hormonal Balance for Improved Fertility.

      Best wishes!

  31. I have used DIM to help with fertility and I have been pregnant twice this year. Last time I stopped the DIM on the Doctor’s advice and then miscarried a week later. I don’t know if it was related but I’m pregnant again and would like to know whether DIM is safe during pregnancy as I don’t want to stop it. If not which safe hormones should I be prescribed to do the same job?

    • Elizabeth Willett, MA, CH

      Dear Jo!

      First Congratulations on your pregnancy! What wonderful news!

      I am also sorry you are concerned. We suggest stopping the use of DIM when pregnancy is confirmed as well. Through our research we have found no reason to avoid using DIM while trying to conceive. We feel it is fine to continue DIM while trying for a baby, but suggest it be discontinued once pregnancy is confirmed.

      We have not heard of pregnancy loss as a result of discontinuing the use of DIM in early pregnancy. The reason it is not deemed safe for use in pregnancy by most manufactures is because there is no research to show if it is safe or not. Therefore for liability reasons no one can say it is safe to take in pregnancy. So, it is always best to follow the guidance of your healthcare provider. You should share your concerns with him/her and ask about weaning off of DIM rather than just stopping because stopping its use is concerning you.

      Best wishes!

  32. I have to thank you for this info, I’ve noticed a significant change in my system…and I’m just getting started!!!

  33. in every cycle cyst fomation in my overy obseverd which prevent pregnancy what is correct way to aviod cyst?

  34. I have cyst on my both ovaries and endometriosis which cause me too much pain. So please help me if u have some remedies natural

  35. Please i need more info ovarian cyst

    • Hi leiaka,
      You can learn more about natural therapies for ovarian cysts here: http://natural-fertility-info.com/ovarian-cyst-remedy

    • Hi,

      Is it safe for me to take myo inositol and dim together. My estrogen is not high but i do have high androgens and high prolactine that i think it is preventing me to become pregnant.
      So can i take both and will dim make my estrogen go to low (i dont want that to happen) .
      thanks,

      Catarina

    • Dear Catarina,

      Myo-Inositol and DIM can be combined. DIM works to help the body metabolize excess estrogens, those bad estrogens, and is not known to impact the estrogen a woman needs, her endogenous, good estrogens.

      Consider also learning more about the Fertilica Vitex.