How to Use Systemic Enzyme Therapy to Increase Your Fertility…

How to Use Systemic Enzyme Therapy to Increase Your Fertility…

What are Enzymes?

Occurring in every living thing on earth, enzymes are biological molecules that catalyze (increase the rate of) chemical reactions. Almost all chemical reactions in the cell need enzymes in order to occur at rates sufficient for life. They build new proteins, cells, tissues and organs, and also tear down these same tissues.

The ability to ward off disease, repair injuries and sustain the body’s homeostasis are all connected to the concentration and strength of enzymes we have in our bodies. There are over 3,000 different types of enzymes in the human body constantly at work initiating millions of chemical reactions every second in the human body. If we did not have enzymes there would be no digestion, no blood coagulation, no reproduction, no breathing and no use of the senses. This gives you an idea of how important enzymes are for the body.

In the body there are many different types of enzymes. We have all heard about digestive enzymes, which help us to digest our food, but there are enzymes that help with all the other functions of the body as well, these are called systemic enzymes. Systemic enzymes work on the entire system.

Benefits of Systemic Enzymes

Systemic enzymes have been studied and shown to provide many benefits beneficial for healthy fertility.

Some of the beneficial actions systemic enzymes have within the body are to counteract chronic inflammation, reduce the substances in the blood that trigger an hyper-autoimmune response, break down fibrin (the substance that scars are made from) and improve blood flexibility and flow. All of these actions can help to support healthy reproductive function.

Anti-Inflammatory Effect
Systemic enzymes help to break down the substances in the blood that create inflammation and infection. This may benefit those experiencing inflammation from endometriosis by reducing the inflammation caused from the scar tissue irritating the surrounding organs and may help with the pain that sometimes comes from having endometriosis.

Regulatory Effect on the Immune System
Systemic enzymes help support the body to reduce a hyper-immune response in the body. One study has shown that they may help to prevent the rejection of the fetus (recurrent miscarriage) and help with other issues related to reproductive immunological imbalances.

Systemic enzymes have also shown to benefit autoimmune hypothyroidism – Hashimoto’s. One study noted that taking Wobenzym resulted in a reduction of autoimmune antibodies that attack the thyroid. Hypothyroidism can be a cause of infertility or recurrent miscarriages.

Breaks Down Scar Tissue
Some systemic enzymes have the ability to break down fibrin, the substance that makes up scar tissue. Scar tissue and adhesion causing fertility issues can form for a variety of reasons including uterine fibroids, pelvic surgery such as Cesarean Section, PID, damage to fallopian tubes, ovarian cysts, endometriosis, IUD, or abortion.

How systemic enzyme blends eliminate scar tissue:

  • The systemic enzyme blend works as a biological response modifier; working with the bodies own immune defense system to moderate inflammatory response.
  • They support cleansing of the tissues, promote better circulation.
  • They break down and remove “fibrin”, the make-up of prolonged inflammation and scar tissue/adhesion formation.
  • They break down the proteins in the blood that cause inflammation, this facilitates their removal via the lymphatic and circulatory system.
  • Reduction in inflammation , increase in proper blood formation, increase in proper circulation hinders scar tissue and adhesion formation, while reducing pain.

Improves Blood Flow

Systemic enzymes cleanse the blood, promotes circulation an stimulates the formation of new, healthy tissue.

Proteolytic enzymes improve blood flow by increasing the flexibility of red blood cells, inhibiting the aggregation of platelets, and helps to prevent abnormal blood clotting. Systemic enzymes also help to support the cleansing of the tissues and promotes better circulation as well as stimulating formation of new, healthy tissue. Simplified they make the blood less “sticky”. This is beneficial for reproductive health in many ways.

The blood cleansing actions of systemic enzymes help to bring proper circulation to the reproductive system and get the “stagnant blood” cleared out helping to remove toxins and also bringing fresh oxygenated blood to your uterus, ovaries and eggs. Imbalances which are considered stagnant are endometriosis, PCOS, heavy dark menses, ovarian cysts and uterine cysts. The fresh oxygenated, free flowing blood is also able to transport more nutrients to the eggs, supporting egg health.

Types of Systemic Enzymes and Their Actions:

The benefits mentioned above have been validated through studies done over the last 40 years on an enzyme blend containing these specific enzymes:

  • Bromealin: Breaks down protein and is a beneficial as an anti-inflammatory.
  • Chymotrypsin: Breaks down proteins, primary anti-fibroid enzyme and has a beneficial effect on the blood. It also works as a catalyst joining the actions of all the enzymes in the blend.
  • Pancreatin: A combination of pancreatic enzymes secreted by the pancreas. Made up of amylase, lipase and protease. These enzymes help to break down carbohydrates, regulates histamine, breaks down fats, helps reduce cholesterol, supports hormone production, bonds with alpha 2-macro-globulin to support immune function, reduces inflammation and increases circulation.
  • Papain: Extracted from papaya, papain breaks down protein and is most beneficial as an anti-inflammatory.
  • Rutin: Breaks down protein and is as beneficial as an anti-inflammatory.
  • Trypsin: breaks down proteins and can have beneficial effects on the blood, such as reducing the risk of blood clots.

Systemic Enzyme Therapy for Fertility

Systemic Enzyme Therapy is a natural method utilizing these unique enzymes to help support reproductive health and fertility. There are many fertility issues that may be supported with the use of systemic enzymes. Plan on using them for at least 3 months or more before you begin trying to get pregnant, depending on how long the issues has been around. Here are some of the issues systemic enzymes may help with:

Systemic Enzyme Therapy is one of the best and most effective natural therapies for endometriosis. Systemic enzymes may help to reduce the scar tissue and breakdown the excess tissues left from endometriosis.

Systemic Enzyme Therapy may also aid women who have endometriosis by reducing the inflammation caused from the scar tissue irritating the surrounding organs and may help with the pain that sometimes comes from having endometriosis.

The blood cleansing actions of this therapy help to bring proper circulation to the reproductive system and get the “stagnant blood” cleared out, bringing fresh oxygenated blood to your uterus and ovaries.

For this purpose it is best to start the Systemic Enzyme Therapy with The Fertility Cleanse. For endometriosis it is suggested to stay on the Systemic Enzyme Therapy for at least three months prior to trying to get pregnant so all of the stagnant tissues and scar tissues can be cleared.

Recurrent Miscarriage
For recurrent pregnancy losses caused from either immunological response or blood clotting, Systemic Enzyme Therapy is an affective option. In a five year study women who had experienced a recurrent miscarriage due to immunological response (more than 30% of miscarriages) were put on a systemic enzyme supplement before and during there pregnancies(1). 79% of the women carried out their pregnancies to term and gave birth to healthy babies. This is an amazing discovery. The only options available before this study were anti-immunological agents similar to the type used in transplant patients, but most doctors will not use them due to there toxicity during pregnancy.

The best product we have found and the product that was actually used in the study mentioned above is Wobenzym N. It is the only systemic enzyme product that has been studied and used during pregnancy. You can also use this study if you would like to talk to your doctor about using this product during pregnancy.

Uterine Fibroids and Cysts
The systemic enzymes have been shown in research to reduce the engorgement (swelling and pain) of fibrocystic conditions. They also eat away at the cysts reducing their size or eliminating them over time. With uterine fibroids it is important to also make sure you are reducing your estrogen exposure and actively getting rid of excess estrogens, this can be done with the estrogen metabolizer DIM.

Using Systemic Enzyme Therapy is one of the two most important natural therapies for uterine fibroids. I have not found a more powerful way of reducing or supporting the body in eliminating uterine fibroids.

Old Scar Tissue and Blocked Fallopian Tubes
Systemic Enzyme Therapy can help to reduce the scar tissues left from surgeries like cesareans, PID, tubal reversal, abdominal surgery, etc. which may be affecting your reproductive system. Specific systemic eat away and reduces the fibrin (the material that makes up scar tissue) over time. This therapy is extremely effective at reducing scar tissues.

Scar tissue and adhesion causing fertility issues can form for a variety of reasons: uterine fibroids, pelvic surgery such as Cesarean Section, PID, damage to fallopian tubes, ovarian cysts, endometriosis, IUD, or abortion.

Pelvic Inflammatory Disease
A systemic enzyme blend was studied and found to be as effective as medication at helping the body to overcome Pelvic Inflammatory Disease (PID). PID is a general term used to describe inflammation of the uterus, ovaries, and/or fallopian tubes. PID can be cuased by parasitic, viral, fungal, but most often through bacterial infection. If left untreated PID can lead to scar tissue and adhesion formation. If PID advances to this stage it may lead to blocked fallopian tubes and sterility in women. PID often comes from Sexually Transmitted Disease (STD’s). 2/3 of women who have undergone laparascopic surgery to determine infertility cause who were found to have PID were unaware they even had PID.

A randomized double -blind study was performed on 100 women with Pelvic Inflammatory Disease. One group was given 5 tablets of Wobenzym N, three times a day. The control group was given an NSAID drug in the usual dosage. Both groups were also given antibiotics (PID requires antibiotics). The patients were given the treatment for 16 or 17 days. Wobenzym N performed with amazing results in fighting damage to tissues, pain, inflammation and overall pelvic congestion. 57% of women using Wobenzyme N were without any complaints, whereas only 6% of women who took NSAIDs were without complaints. Overall, 100% of the the patients who use Wobenzyme N reported their condition as substantially improved, compared to only 73.5 % using the NSAIDs. In addition studies have shown Wobenzym N enhances the body’s response to use of antibiotic medications.

Supporting Egg Health
One of the major factors for increasing egg health is to increase the circulation to the ovaries. Systemic Enzyme Therapy can help to cleanse the blood, increase circulation and make the blood less “sticky”. For best results use the Systemic Enzyme Therapy in conjunction with the OvaWise Health Program.

How to Use Systemic Enzymes

For the best results you must take a high quality systemic enzyme that contains the specific enzymes listed in the ‘Types of Enzymes’ list. The one we feel is the best is the enzyme blend that was used in the studies mentioned through out this guide and has been studied and used for over 40 years – Wobenzym N.

“Wobenzym N is the most thoroughly researched enzyme mixture available worldwide. Wobenzym N contains five potent enzymes including pancreatin, trypsin, chymotrypsin, bromelain, and papain, as well as the bioflavanoind rutin. Wobenzym is clearly the most scientifically and clinically validated enzyme formula in the world.” -Michael Loes, M.D., M.D. (H.)

Wobenzym N combines all the beneficial delicate enzymes and is protected by a vegetable-based enteric coating which ensures optimal absorption and utilization in the blood stream.

Suggested Usage: Adults take three (3) tablets, twice daily, on an empty stomach, with water at least 45 minutes before meals and 2 hours after eating to take your enzymes.

Advanced usage: Adults may gradually increase to 12 per day by taking 3 tablets 4 times per day on an empty stomach.

Take on an empty stomach: This is very important. The enzymes need to make it past the stomach to be absorbed in the intestine. Do not take with food. Wait at least 45 minutes before eating and 2 hours after eating to take your enzymes.

Safety & Side Effects

There has been no toxicity shown from using systemic enzymes. There is no dangerous or lethal dose of systemic enzymes. These enzymes are the same enzymes the body naturally contains. Wobenzym can be used in preconception and has been shown to be helpful throughout pregnancy (see above information) with the agreement/approval of your doctor.

Stop taking systemic enzymes two weeks prior to any type of surgery. Use systemic enzymes in preparation for conception, not while you are pregnant or may be pregnant. If you are using Wobenzym for possible miscarriage prevention, please talk with your doctor and get their approval for use during pregnancy.

Use During Pregnancy

Wobenzym can be used in preconception and has been shown to be helpful throughout pregnancy to help prevent recurrent miscarriage due to immunological imbalances (see study under Recurrent Miscarriage section) with the agreement/approval of your doctor. Please consult with your doctor or midwife before using any supplements during pregnancy.

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  1. Hi, I was wondering if I can do systemic enzyme therapy (take Wobenzym) while doing a fertility cleanse?

    • Elizabeth Willett, MA, CH

      Hello Nancy!

      Yes, you can take Wobenzym N while doing the Fertility Cleanse. Wobenzym N can be taken all cycle long unless you have heavy menstrual bleeding in which case it should be avoided during menstruation.

      Be well!

  2. Dear Elizabeth,

    I have recently been diagnosed with having 2 ovarian cysts (each about 4cm and 5 cm). And currently i am suffering from hypothydrodism. My gynae has put me on 3 months contraceptive pills to monitor the cysts. As such, i am wondering during this period would it be advisable for me to take Wobenzym?

    Would appreciate your advice greatly.

    Thanks you,

    • Elizabeth Willett, MA, CH

      Hello FL!

      Wobenzym N can be taken with contraceptive pills, but it is always best to discuss all that you are taking and doing to support your fertility/fertility issue with your healthcare provider. While Wobenzym N is part of the ovarian health program it is best to use the entire program. You can learn more about supporting ovarian health here…

      You might also like to read for additional guidance.

      I wish you well!

  3. Dear Elizabeth,

    Is it proven that Wobenzym N can actually break down existing adhesions and are already formed?

    Also I have just started taking a daily does of Vitamin E, vitamin B complete, Iron, Shatavari power, and respberry leaf tea. In to hope of rebuilding my uterine lining. Would it be too much to take the Wobenyzme N on top? is it all to much for my body to break down?

    Kind regards


    • Elizabeth Willett, MA, CH

      Hello again Lisa!

      Years of scientific research has shown Wobenzym N efficient in supporting a number of fertility issues. Please take a bit of time to read at length about this research and the Fertility Benefits of Wobenzym N here…

      Wobenzym N can be combined with Vitamin E, a Vitamin B complex, Iron, Shatavari and Red Raspberry Leaf tea without concern.

      In health ~ Liz

  4. Hi Dalene and Elizabeth.

    I have recently been diagnosed with adhesions in my uterus and 4 mm endometrium after a d&c. I have been suffering for severe pain during ovulation and during period. I am suffering from pain in my uterus and ovaries. Can you recommend a blend of Systemic Enzyme Therapy that will help break down adhesions and help rebuild the lining of my uterus.

    Thank you kindly

    • Elizabeth Willett, MA, CH

      Dear Lisa,

      The product we support for use in Systemic Enzyme Therapy for fertility is Wobenzym N. Wobenzym N in part support the body’s ability to break down fibrin (the substance that makes up scar tissue), encourages normal circulation to the reproductive system, which in turn supports a healthy vibrant uterus and uterine lining, and supports the body’s natural inflammation response, providing relief for occasional discomfort in the reproductive system.

      Take time to also learn additional ways to build the uterine lining naturally.

      You might also appreciate Women’s Best Friend Lisa. This herbal combination supplement combines herbs to reduce occasional discomfort and swelling of the female reproductive system.

      Take care!

  5. I am a 50year old woman., I have been recently tested for fibroids in my uterus (3)and my left fullopian tube is swollen shut and my left ovarie is closed also has (2) cys mass on it 1- is 5.8cm,and 1- is 4.0cm and I don’t have a right Fallopian tub it was removed 5yrs a go, but I have my right ovarie but it is closed they want to do a total hysterectomy,is there anything I can take that will prevent this from happying. Thank you for your time,. -teresa

  6. Hello

    I’m 43 years old had multiple miscarriages which lead to me having to undergo three operations 2 myomectomies in 1999 and 2012 and one UAE (Embolization) in 2009. I recently did an HSG to see my tubes are block since I was not getting pregnant, the findings of the HSG is that the ” uterine cavity is not well outlined with concern for synechiae. Contrast spillage into the peritoneum is evident denoting patency” i then had uterine evaluation by Hysteroscopy the findings are fixed atrophic uterus – Ashermans. An ultraSound show there is marked UAE effect and dense fibrotic rings around the endo/myo junction. Can I try enzyme therapy my only option is surrogacy and we do not want to go

    • Elizabeth Willett, MA, CH

      Hi Brenda!
      I am sorry you have had to go through all of this!

      Systemic Enzyme Therapy has been shown to be supportive in part in certain cases of the body’s ability to break down fibrin (the substance that makes up scar tissue), normal circulation to the reproductive system, aiding the body’s natural ability to reduce tissue buildup in the uterus and the body’s natural inflammation response, providing relief for occasional discomfort in the reproductive system.

      Fallopian tubes and a uterus that are severely damaged need special care. In those cases we would suggest you work with a specialist. A specialist will be able to evaluate your unique situation and determine the best possible course of care. Clear Passage Physical Therapy Clinics may be one option.

      The good news is that natural therapies can be used alone, or alongside any type of treatment options you may consider, which may greatly help to improve outcome.

      I wish you well!

  7. how long do you take the wobenzym n and I read something about not taking when menstruating..please advise.

    • Hi Shandrea,

      Wobenzym N used as systemic enzyme therapy is best avoided during menstruation by women with heavy menstrual cycles. Wobenzym N has a slight blood thinning action, which may potentially cause heavier menstrual bleeding.

      Wobenzym N is best used therapeutically for at least 3-6 months consistently, or as directed by your healthcare provider.

      All the best!

  8. I have Ashermans syndrome and would like to try enzyme therapy. Can I take Wobenzym N while doing the fertility cleanse or is it best to do the cleanse first?

    • Hi kristie,

      Wobenzym N is fine to combine with the Fertility Cleanse Kit products. Let us know how it works for you and thank you for contacting us!

  9. Hello

    I have many ovarian cyst and they are 10cm in diameter. I have hypothyroism and are now having a big hormon/liver and gallbladerdetoxs and are also trying to get my metabolism in order with mineralterapi. I dont know what kind of cyst i do have. You named tre types that maybee doesent answer to your treatment, should I Be worried? My doc were very arogant and wanted to surgey them out, but I dont trust these doctors with knives. Can you tell me about your experients of cyst in this sizes?? I love your site! Thank your for everything, this is giving my hope!

    • Hi Elisabeth,

      You said that you have many ovarian cysts that are all 10cm? 10cm is quite large for one ovarian cysts alone, but to have many that size threatens permanent damage or even the loss of the ovary. If you are uncomfortable with your doctor, you may want to seek a second opinion. At the very least, I encourage you to open a line of communication with your doctor or his lead nurse, so you can find out what type of cysts you have and what the risks are to your health to not have surgery performed. It is true that complex cysts, as some are named in this article, often don’t respond to the natural therapies listed in this article as well as functional ovarian cysts do. This is why it is important to find out the type of cysts you have.

      I hope this helps you to make a decision. Be well :)

  10. Hello, I would like to avoid surgery to remove fibriods for a second time and I would like to have my tubes unblocked in order to conceive without IVF treatment. In addition to Wobenzym N, to be precise, what other products should I take along with it and how can I purchase them. More of your advice and suggestions are appreciated. Thank you kindly.

    • Hi Ruth,

      You can learn natural options for uterine fibroids here:

      Learn natural support options for fallopian tube health here:

      Fallopian tubes that are severely damaged need special care. In those cases we would suggest you work with a specialist. A specialist will be able to evaluate your unique situation and determine the best possible course of care. Clear Passage Physical Therapy Clinics are a great option for those who do not want surgery. It is important to recognize that the fallopian tubes are about the size of a spaghetti noodle in width and are very delicate. Any sort of trauma can alter their function and damage the tubal tissues. Once they are damaged it may be difficult to reverse that damage. In that case, only IVF is an option for achieving pregnancy.

  11. Hi
    I am going for an operation to remove scar tissues from my womb. I have ashermans syndrome . When can I start taking this to help prevent /reduce regrowth ?

    • Elizabeth Willett, MA, CH

      Hello Nellie ~ It is best to wait to begin using Systemic Enzyme Therapy until you have healed from surgery. For each person this is different, but in general 2-3 weeks. Wobenzym N, which is the enzyme blend used in this therapy, is not intended for use during times of heavy bleeding (menstruation and otherwise). Best wishes for an easy, quick procedure and speedy healing!

  12. Hi
    I wda diagnosed epidadmes obstruction azopspermia
    Can you help me what remove my obstruction.

  13. Can I make an order of the enzymes and get it delivered to Lagos, Nigeria? I am 30 years, and I have been battling ovarian cysts and endometriosis for a while. I would be getting married in 3 months and 3 weeks and I would prefer to use natural remedies instead of surgery in taking care of this problem and boosting my fertility. How can you help?
    Thank you.

    • Hi Daisy,

      Congratulations on the wedding news! Please contact our customer service regarding shipping options for Nigerians.

      A consultation with one of our herbalists may greatly help you to know what natural therapies are best for your needs. To be honest sometimes surgery is necessary to improve health. The stage of endometriosis you are in will play a huge role in how well the body will respond to natural therapies for these conditions. In advanced cases, it may be best to consider medical options combined with natural therapy options.

  14. dear Hethir
    I ve made up mind to go for sugery again to remove fibroids so that I can have children, at what point do I start taking wobenzym n to prevent scar tissues and adhesions. I have also ordered for the fertility cleanse, castor oil pack and the massage dvd
    Thanking you for your response

    • Hi Nana,

      Systemic Enzyme Therapy using Wobenzym N should be discontinued 2 weeks prior to surgery and not begun again for at least 2 weeks post-operation. It is best to not begin any of the other therapies until you are fully healed from surgery, so 2 weeks to a month post operation. Take it easy, go slow. Sending you blessings for your upcoming procedure.

  15. Do you have a kit for systemic enzyme therapy?