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How to Use Systemic Enzyme Therapy to Increase Your Fertility…

How to Use Systemic Enzyme Therapy to Increase Your Fertility…

What are Enzymes?

Occurring in every living thing on earth, enzymes are biological molecules that catalyze (increase the rate of) chemical reactions. Almost all chemical reactions in the cell need enzymes in order to occur at rates sufficient for life. They build new proteins, cells, tissues and organs, and also break down these same tissues.

The ability to ward off disease, repair injuries and sustain the body’s homeostasis are all connected to the concentration and strength of enzymes we have in our bodies. There are over 3,000 different types of enzymes in the human body, constantly at work initiating millions of chemical reactions every second. If we did not have enzymes there would be no digestion, no blood coagulation, no reproduction, no breathing and no use of the senses. This gives you an idea of how important enzymes are for the body.

In the body there are many different types of enzymes. We have all heard about digestive enzymes, which help us to digest our food, but there are enzymes that help with all the other functions of the body as well, these are called systemic enzymes. Systemic enzymes work on the entire system.

Benefits of Systemic Enzymes

Systemic enzymes have been shown beneficial for healthy fertility.

Systemic enzymes have been shown beneficial for healthy fertility.

Some of the beneficial actions systemic enzymes have within the body are to counteract chronic inflammation, reduce the substances in the blood that can trigger a hyper-autoimmune response, break down fibrin (the substance that scar tissue is made from), and improve blood flexibility and flow. All of these actions can help to support healthy reproductive function.

Anti-Inflammatory Effect
Systemic enzymes help to break down the substances in the blood that create inflammation and infection. This may benefit those experiencing chronic inflammation related to a fertility issue such as endometriosis, uterine fibroids, PID or ovarian cysts.

Chronic inflammation can be caused from and cause injury to the healthy tissues of the reproductive system that are being invaded by foreign tissue or infection. Inflammation and foreign tissue growth can create scar tissue and adhesion formation in the reproductive organs and the surrounding structures within the abdominal cavity. Inflammation can also cause pain. Pain is a common problem for women with chronic inflammation due to fertility issues, especially endometriosis and uterine fibroids. Reducing inflammation with Systemic Enzyme Therapy may in turn help reduce pain.

Regulatory Effect on the Immune System
Systemic enzymes help the body to reduce the occurrence of a hyperimmune response. One study has shown that they may help to prevent the rejection of the fetus (recurrent miscarriage) and help with other issues related to reproductive immunological imbalances.

Systemic enzymes have also been shown to benefit autoimmune hypothyroidism – Hashimoto’s. One study noted that taking a systemic enzyme blend resulted in a reduction of autoimmune antibodies that attack the thyroid. Hypothyroidism can be a cause of infertility or recurrent miscarriages.

Breaks Down Scar Tissue
Systemic enzymes have the ability to break down fibrin, the substance that makes up scar tissue. Scar tissue and adhesion causing fertility issues can form for a variety of reasons including uterine fibroids, pelvic surgery such as Cesarean Section, PID, damage to fallopian tubes, ovarian cysts, endometriosis, IUD, or abortion.

How systemic enzyme blends eliminate scar tissue:

  • The systemic enzyme blend works as a biological response modifier; working with the bodies own immune defense system to moderate inflammatory response.
  • They support cleansing of the tissues and promote better circulation.
  • They break down and remove “fibrin”, the make-up of prolonged inflammation and scar tissue/adhesion formation.
  • They break down the proteins in the blood that cause inflammation, this facilitates their removal via the lymphatic and circulatory system.
  • They support a reduction in inflammation, an increase in proper blood formation, and an increase in circulation which helps to hinder scar tissue and adhesion formation, while also reducing pain.

Improves Blood Flow

Systemic enzymes cleanse the blood, promote circulation and stimulate the formation of new, healthy tissue.

Proteolytic enzymes improve blood flow by increasing the flexibility of red blood cells, inhibiting the aggregation of platelets, and helping to prevent abnormal blood clotting. Systemic enzymes also help to support cleansing of the tissues and promote better circulation as well as stimulate formation of new, healthy tissue. Simplified they make the blood less “sticky”. This is beneficial for reproductive health in many ways.

The blood cleansing actions of systemic enzymes help to bring proper circulation to the reproductive system and get the “stagnant blood” cleared out, helping to remove toxins and also bringing fresh oxygenated blood to your uterus, ovaries and eggs. Imbalances which are considered stagnant are endometriosis, PCOS, heavy dark menses, ovarian cysts and uterine fibroids. The fresh oxygenated, free flowing blood is also able to transport more nutrients to the eggs, supporting egg health.

Types of Systemic Enzymes and Their Actions:

The benefits mentioned above have been validated through a variety of studies and clinical use on the following enzymes:

  • Serratiopeptidase (Serrapeptase) breaks down proteins, fibrin and mucus, to support the body in maintaining normal blood flow/circulation to the reproductive organs, aid in healthy fluid retention and support a healthy inflammatory response.
  • Bromelain, extracted from the core and stem of the pineapple, breaks down protein and is beneficial as an anti-inflammatory.
  • Protease digest proteins to help improve the body’s immune system response to invaders; invaders are proteins in the form of fibrin which is the tissue that makes up a scar, some blood clots and Candida overgrowth.
  • Nattokinase enhances the body’s production of plasmin, the enzyme that dissolves and breaks down fibrin, to support healthy scar tissue formation by the body, while supporting heart health and healthy blood clotting.
  • Lipase breaks down fats for proper absorption in the intestines supporting the body’s ability to properly absorb fat which is very important for reproductive health; helps the body achieve optimal pH balance and maintain a healthy weight.
  • Amylase breaks down carbohydrates helping the body regulate glucose levels and achieve optimal Ph balance, both necessary for healthy fertility; healthy blood and environment within the female reproductive organs.
  • Papain, extracted from papaya, breaks down protein and is most beneficial as an anti-inflammatory.

These specific enzymes have been combined in a systemic enzyme blend formulated specifically for fertility; see it here…

Important note: Both amylase and lipase help improve the breakdown and absorption of food nutrients to free up pancreatic enzymes for boosting immune and inflammatory responses, and fight toxin build up with the body.

Systemic Enzyme Therapy for Fertility

Systemic Enzyme Therapy is a natural method utilizing these unique enzymes to help support reproductive health and fertility. There are many fertility issues that may be supported with the use of systemic enzymes. Plan on using them for at least 3 months or more before you begin trying to get pregnant, depending on how long the issues have been around. Here are some of the issues systemic enzymes may help with:

Endometriosis
Systemic Enzyme Therapy is one of the best and most effective natural therapies for endometriosis. Systemic enzymes may help to reduce scar tissue and breakdown the excess tissues left from endometriosis.

Systemic Enzyme Therapy may also aid women who have endometriosis by reducing the inflammation caused from the scar tissue irritating the surrounding organs and may help with the pain that sometimes comes from having endometriosis.

The blood cleansing actions of this therapy help to bring proper circulation to the reproductive system and get the “stagnant blood” cleared out, bringing fresh oxygenated blood to your uterus and ovaries. For this reason, consider starting a natural fertility program for endometriosis with The Fertility Cleanse and when that is complete, Systemic Enzyme Therapy and other natural therapies can be started.

For endometriosis it is suggested to stay on the Systemic Enzyme Therapy for at least three months prior to trying to get pregnant so all of the stagnant tissues and scar tissues can be cleared.

Recurrent Miscarriage
For recurrent pregnancy losses caused from either immunological response or blood clotting issues, Systemic Enzyme Therapy is an effective option. In a five year study, women who had experienced recurrent miscarriage due to immunological response (more than 30% of miscarriages) were put on a systemic enzyme supplement before and during their pregnancies. 79% of the women carried out their pregnancies to term and gave birth to healthy babies. (Forum Immunologie, 2000) This is an amazing discovery. The only options available before this study were anti-immunological agents similar to the type used in transplant patients, but most doctors will not use them due to their toxicity during pregnancy.

If you have immune-related infertility and are interested in taking systemic enzymes into your pregnancy, talk to your healthcare provider and ask for guidance.

Uterine Fibroids and Cysts
Systemic enzymes have been shown in research to reduce the swelling and pain associated with fibrocystic conditions. They also help the body through its own mechanisms to reduce and eliminate cysts over time. With uterine fibroids, it is important to also make sure you are reducing your estrogen exposure and actively getting rid of excess estrogens, this can be done with the estrogen metabolizer, DIM.

Using Systemic Enzyme Therapy is one of the most important natural therapies for uterine fibroids. I have not found a more powerful way of reducing or supporting the body in eliminating uterine fibroids.

Old Scar Tissue and Blocked Fallopian Tubes
Systemic Enzyme Therapy can help to reduce the scar tissue, which may be affecting your reproductive system. Systemic enzymes eat away and reduce the formation of fibrin (the material that makes up scar tissue) over time, making this therapy extremely effective at reducing scar tissue.

Scar tissue and adhesion causing fertility issues can form for a variety of reasons: uterine fibroids, pelvic surgery such as Cesarean Section, PID, damage to fallopian tubes, ovarian cysts, endometriosis, IUD, D&C, or abortion.

Pelvic Inflammatory Disease
Systemic enzymes may be effective as medication at helping the body to overcome Pelvic Inflammatory Disease (PID). PID is a general term used to describe inflammation of the uterus, ovaries, and/or fallopian tubes. PID often comes from Sexually Transmitted Disease (STD’s), and can be caused by parasitic, viral, fungal, but most often from bacterial infection. If left untreated, PID can lead to scar tissue and adhesion formation. If PID advances to this stage it may lead to blocked fallopian tubes and sterility in women. Two thirds of women who have undergone laparoscopic surgery to determine infertility cause who were found to have PID were unaware they even had PID.

A randomized double-blind study was performed on 100 women with PID. One group was given 5 tablets of systemic enzymes three times a day. The control group was given an NSAID drug in the usual dosage. Both groups were also given antibiotics (PID requires antibiotics). The patients were given the treatment for 16 or 17 days. The systemic enzyme blend performed with amazing results in fighting damage to tissues, pain, inflammation and overall pelvic congestion. 57% of women using systemic enzymes were without any complaints, whereas only 6% of women who took NSAIDs were without complaints. Overall, 100% of the the patients who used systemic enzymes reported their condition as substantially improved, compared to only 73.5 % using the NSAIDs.

Supporting Egg Health
One of the major factors for increasing egg health is to increase the circulation to the ovaries. Systemic Enzyme Therapy can help to cleanse the blood, increase circulation and make the blood less “sticky”. For best results use the Systemic Enzyme Therapy in conjunction with the OvaWise – Egg Health Program.

How to Use Systemic Enzymes

For the best results you must take a high-quality systemic enzyme blend that contains the specific enzymes listed in the ‘Types of Enzymes’ list above. The one we feel is the best is the only fertility-specific enzyme product in existence, Fertilica Choice EnzymesTM.

Fertilica Choice EnzymesTM is specifically formulated to be a great ally for many fertility health issues using plant-sourced systemic enzymes in a vegetable-based enteric coating which ensures optimal absorption and utilization in the blood stream.

Suggested Usage: Adults take three (3) tablets daily with water, on an empty stomach. To ensure you have taken the tablets on an empty stomach, take Fertilica Choice EnzymesTM at least 45 minutes before meals, or 2 hours after eating a meal.

Take on an empty stomach: This is very important. The enzymes need to make it past the stomach to be absorbed in the intestine. Do not take with food. Wait at least 45 minutes before eating and 2 hours after eating to take your enzymes.

Safety & Side Effects

There has been no toxicity shown from using systemic enzymes. There is no dangerous or lethal dose of systemic enzymes. These enzymes are the same enzymes the body naturally contains. Fertilica Choice EnzymesTM can be used for preconception. Talk to your doctor about continuing any systemic enzyme blend throughout pregnancy (see above information) and do so only with the agreement/approval of your doctor.

Stop taking systemic enzymes two weeks prior to any type of surgery. It is best to begin use of systemic enzymes in preparation for conception for best results. If you are using systemic enzymes for possible miscarriage prevention, please talk with your doctor and get their approval for use during pregnancy.

Use During Pregnancy

Systemic enzymes can be used in preconception and have been shown to be helpful throughout pregnancy to help prevent recurrent miscarriage due to immunological imbalances (see study under Recurrent Miscarriage section) with the agreement/approval of your doctor. Please consult with your doctor or midwife before using any supplements during pregnancy.

Too learn more about related subjects covered in this article, please visit the following links:

Immune Infertility: Natural Options for Immunological Fertility Issues

How Hashimoto’s Thyroiditis Affects Fertility

Estrogen Fertility Guide

Serrapeptase for Fertility Issues

Our Complete Library of Fertility Issues

References

  • Baker, A. (2016, March 09). Digestive Enzymes & Immunity: Making the Connection. Retrieved from http://nourishholisticnutrition.com/digestive-enzymes-immunity-making-the-connection/
  • Bohager, T. (2009) Everything You Need to Know About Enzymes. Austin, Texas: Greenleaf Book Group Press.
    ­

  • Chichoke, A. (2000). Enzymes & Enzyme Therapy ­ how to jump­start your way to lifelong good health. Second Edition. Chicago: Illinois: Keats Publishing. pp 199­200.
  • Chichoke, A. (1999) The Complete Book of Enzyme Therapy. New York, New York: Avery.
  • Dittmar, F­W. (3/2000) Enzyme therapy ­ a method of immune therapy for women with a history of immunologically ­induced habitual abortion. Foum Medizin Verlagsgesellschaft, Forum Immunologie.
  • Dittmar, F.­W., W. Luh. (1993) Treatment of fibrocystic mastopathy with hydrolytic enzymes. International J. of Experimental and Clinical Chemotherapie; Vol. 6, No. 1, pp. 9­20
  • Enzymes & Enzyme Therapy; How to jump­start your way to lifelong good health. Second Edition. Chicago: Illinois: Keats Publishing. pp 199­200.
  • Friedrich F. Wobenzym® in the Treatment of Chronic Pelvic Inflammatory Disease. Germany Report provides through: PHARMASCRIPT, Kathi­Kobus­Steig 1, W­8190. Study Number: MU­89210.
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  • Kvantchakhadze, R. G. (2002). Wobenzym in the complex treatment of autoimmune thyroiditis. International Journal on Immunorehabilitation, 4(1), 114.
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  • Loes, M. (2010) The New Aspirin Alternative. Freedom Press.
  • Nouza K., Madar J. VIII. (2001) Immunomodulation in the treatment of reproduction disturbances. American Journal of Reproductive Immunology; Vol. 46, No. 1, pp. 106, Abst. WP8­3
  • Nouza, K., Kinsky, R., Dimitriov, D. (1992) Immunology and immunopathology of reproduction. Folia Biologica; 38, Prag. Inderst, R. (1990) Enzyme therapy in vascular disease. Allgemeinmedizin; 19,154.
  • Papain. (n.d.). Retrieved from http://www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/analytical-enzymes/papain.html#application
  • Patki, V, M.D. How Systemic Enzymes Fight Inflammation. Retrieved from http://www.systemicenzymetherapy.com/Inflammation/CourseofAction.htm
    ­

  • Ruhter, E. and Warner, N. (2010). Nutrition & Herbs For Chronic Musculoskeletal Pain. Minnesota.
  • Serafini,C. (n.d.) D.C. Systemic Enzymes, Lignans and Uterine Health. PDF
  • Willett, E. (n.d.) Is Serrapeptase the Right Enzyme Therapy for Fertility Issues? Retrieved from http://natural-fertility-info.com/serrapeptase-enzyme-therapy.html
  • Yeah We Have an Enzyme for That. (2010). Enzymedica Educational Material (brochure)

Comments

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[-] 292 Comments
  1. Due to the blood thinning effects systemic enzymes have, is it recommended to stop taking the enzymes during menstruation? I’m wondering if taken during menstruation, would cause heavier menstrual flow.

    • Dear Michelle,

      This is only necessary for someone who already experiences heavy menstrual flow. If flow is light or normal, someone could continue enzymes during menstruation.

  2. Do I need to wait 45 minutes after taking the enzymes to drink anything or is it ok to drink my tea after I take the enzymes?

  3. Thank you for your earlier response Elisabeth! A recent MR scan showed that i have multiple fiboids measuring from 0.5 – 7 cm. Also have had continuous bleeding for 3 months. A few months ago i made some diet changes and started supplementing with DIM and turmeric, Vit C, D3, magnesuim, iron ( for the anemia) milk thistle snd probiotics. I would like to consider the systematic enzyme for the fibroids. My bleeding is a lot less now but still there. How do the systematic enzymes (Serratiopeptidase and nattokinase) work with bleeding problems? Would the enzyme act like blood thinner and increase the bleeding issue?

  4. Hello,

    Do you have any ideas on how to prevent ovarian cysts in a 22-year-old with irregular periods? She has no interest in fertility or conception-related issues…just a preventative approach to help ward them off in the future. Thank you!

  5. Hi! I am TTC and started taking your enzymes 1 1/2 months ago for 1 blocked tube. Some days, I have taken 2 pills, but most days, I have only taken 1, to begin slowly. My first period on them came on time, was pretty normal w/ less clots and not quite as heavy. My second period has arrived 10 1/2 days early! I’ve been tracking my cycles for 2 years, and this has never happened (periods are normal.) I was taking OPKs, and although I missed 1 day of them due to being out of town, I never got my positive surge either (also a first.) Could this be a anovulatory cycle? Or should I discontinue? I read blood thinners may cause an early period. Thank you for your advice about your product!

    • Dear Lauren,

      I have not heard of this from systemic enzymes. It would be best to pause enzyme use while bleeding. The body working hard to relearn balance and heal may result in cycle shift. While we know shifts can catch women off guard, we view them as a sign from the body that something is working. Could this bleeding be ovulation spotting at a different time than expected? Can you identify any other changes that could also be a factor – changes in stress levels perhaps? Are you using any other natural therapies or supplements at all?

    • Thanks for your response Elizabeth! It began light but is a medium flow today, so I doubt it would be ovulation spotting. My average cycle is 25-27 days, 11-12 day luteal, so this would make for a 17 day cycle! I have been using MegaFood Prenatal for a year and doing self fertility massage/castor oil for 3 months, starting after period & stopping mid cycle after ovulation. Stress levels have been average & normal. The 1 blocked tube is the only issue I know we are dealing with. Day 3 hormones came back good, have always received positive OPKs in past…this change just concerned me since my cycles appeared in balance before and the enzymes are the newest variable I’ve introduced!

    • Dear Lauren,

      Thank you for sharing these details. I have used systemic enzymes myself without every having a cycle shift and we have not heard of this with Choice Enzymes either, so I am stumped.

      It is of course up to you what you decide to continue to use or not, but if it were me, I would give the enzyme blend more time, see how things go. We know that naturally supporting healthy fallopian tube function and fertility overall takes time and that there can be shifts in the cycles, sometimes completely unrelated to the natural therapies (stress, dietary or hydration level changes, even travel).

      It’d be great to here what you decide to do and how it goes!

  6. Hey!
    I had a miscarriage and I am 38 years old. I do have few fibroids and before I try again I would like to know a natural way to remove those or make smaller . Please help me with your best recommendation. Thank you !

  7. In the past few year I’ve been diagnosed with some many fertility issues that its hard to keep them straight. Once one has been solved it seems like something else comes about. 5 year ago i miscarried at 20 weeks and was told that i have an incompetent cervix, however, this is yet to be confirmed. Since that miscarriage I’ve had 3 more however, all under 9 weeks. 2014: 8 weeks – cause unknown, 2016: 6 weeks – cause possible Ashermans, 2017: 7 weeks – cause possible Endometriosis. I recently had a hysteroscopy done and had some filmy adhesions removed. I am taking systemic enzymes, is it normal to bleed, and how much is normal?

    • Dear Nerissa,

      I’m very sorry to hear of all you’ve been through!

      It isn’t common in general to bleed outside of a normal period or ovulation (ovulation spotting) when taking systemic enzymes. It may be the body healing post adhesion removal. If the bleeding you experience is more than spotting, it would be best to discontinue the enzymes and check just in with your healthcare provider or his/her nurse. Many women with Asherman’s Syndrome and Endometriosis experience irregular bleeding. Indeed challenging!

  8. I am 26 with severe endo, done 2 surgeries to remove chocolate cyst and after that 2 failed IVF. Fast recurring of endo cysts. TTC for 4 years. I can only afford another ivf may be after 1 year. Before that i really want to heal my endo and body through natural way without Lupron. I have done lot of research and found a combination of natural medicines for getting a little relief from endo. So please tell me your suggestions regarding it.
    1. Neprinol
    2. DIM
    3. Phyto Multi (Multi Vitamin)
    4. Pycnogenol
    5. Bee Propolis
    6.Maca Femmenessencee Pro
    7. Omega 3 Krill Oil
    8. Probiotic

    • Hello Irene!

      I’m sorry to hear of all you have been through! It is great you are being so proactive.

      I can not speak to a portion of the supplements on your list. I’m sorry. I don’t have a working knowledge of Neprinol. The others are known to be fertility supportive/protective in many ways. I would suggest also reviewing our guide Chocolate Cysts, Their Fertility Impact and How to Rebalance the Body because we know the body’s response to natural therapies may be better when diet and lifestyle changes to reduce exposure to excess estrogen and support healthy metabolism of xenohormones are made as well.

  9. HOW DO I GET SOME

  10. Hi!
    Recently, I was diagnose with my two tubes blocked. I really think was caused for an abortion I had 16 years ago, when I was 19. Now, the doctor told me that my only option is IFV. First, I would like to try this natural treatment to try to unblocked my tubes. But now I worry about my age (I`m 35). Should I try this natural treatment even when I can loose time while I`m naturally ovulating?
    Also, because I have some problems with my knee I`m taking calcium and glucosamine,chondoitrin sulafte and MSM). It is safe?
    Thanks!

  11. Hi there, I know that Wobenzyme and serraptese need to be taken on an empty stomach. If I’m using them both, can they be taken together at the exact same time?

  12. I have a blood clotting disorder called factor 5 lieden and I take a low dose-aspirin daily. I am now pregnant and can not stop taking the aspirin but I wanted to try to take wobenzym n. Is it harmful to take wobenzym n at the same time as aspirin?

    • Dear Hannah!

      Congratulations on your pregnancy!

      It will be best to ask this question of your healthcare provider. We can not suggest Wobenzym N with low dose aspirin.

  13. Is it ok to take Wobenzym N and Estrogen and Progesterone?

    • Dear Taneeka,

      It would be best to consult your healthcare provider about taking Wobenzym N with estrogen and progesterone if they were prescribed to you (are prescription medications). In general, it is fine to combine them, but your healthcare provider should know all you are taking so as to monitor your success.

  14. Hi,
    I have recently been diagnosed with an ovarian cyst. I have been advised that I have low progesterone levels so I have started taking vitex and dong quai to see if i can improve my progesterone levels and resolve the ovarian cyst.
    Is it ok to take vitex and dong quai at the same time? Or is one better than the other for helping with ovarian cysts? Also, would it be beneficial to try systemic enzymes in conjunction with these herbs?
    Any help would be appreciated 🙂

  15. hi, I just want to find out the Wobenzym N to buy

  16. I’m 26 years old and have never been pregnant. I was diagnosed with blocked fallopian tubes (due to PID) after a hysteroscopy a few years ago. The doctor said that it isn’t impossible to get pregnant, that I have a 10 percent chance but I’m at high risk for an ectopic pregnancy if I do, or I could do IVF. I want to know if this could help me. They say it breaks down scar tissue. I have a bottle of serrapeptase but I promised I wouldn’t take them until I figured out a good diet plan and dedicated myself to it as well as taking the enzymes. Is this a pointless endeavor? I really want to get pregnant and I’ll literally change my entire lifestyle in whatever way I need to just to have a baby.

    • Hi Brittany!

      I would not say ‘pointless’ ever! If you want to conceive naturally and are willing to commit to change, then it my personal opinion that you should go for it. Perhaps you will appreciate the additional tips in our ecoptic pregnancy guide, specifically that under the heading Healing Scar Tissue and Adhesion While Reducing Inflammation. Systemic Enzyme Therapy is discussed there and the enzymes we suggest for this, Wobenzym N, can be used with Serrapeptase. Some to use Serrapeptase alone as well.

      My best! You’ve got this!

  17. Hello, I just tested positive after 9 day embryo transfer. I have had 2 miscarriages in the past and do not know the reason why. One was 22 yrs ago and one was 6 years ago. I have a 22 yr old son. I’m trying to do everything in my power to avoid a miscarriage. Is this safe to take now?

    • Hello!

      Congratulations! What amazing news!

      We suggest being sure to get the agreement/approval of your doctor, but Wobenzym N has been shown to be helpful throughout pregnancy to help prevent recurrent miscarriage due to immunological imbalances (see study under Recurrent Miscarriage section of this article).

      Congrats again and please consult with your doctor or midwife before using any supplements during pregnancy.

  18. I am currently ttc. And am taking quite a few supplements to improve my chances. Was wondering these questions. How long should you be off of low dose aspirin before taking Wobenzym n ? Can it be taken with fish oil ,prenatal vitamins, co q10, inositol, prednisone, IVIG , probiotics, magnesium citrate, vit. D3, calcium , metformin and zinc. I was just prescribed metformin for having a gene mutation of diabetes. Also prescribed prednisone and IVIG. Which are for a gene mutation of Rhumatoid Arthritis. I was hoping the wobenzyme n would be an alternative for metformin, prednisone and IVIG .
    I also have elevated NK cells. Which are possibly caused by the 2 gene mutations.
    Thank you

    • Dear Audrie,

      It is my understanding that Aspirin can stay in the body for a range of time depending on how much is used and for how long. In general, the rule is to be off of aspirin, blood thinners or other NSAID prescribed therapy for 10 days to two weeks before starting Systemic Enzyme Therapy with a blend like Wobenzym N.

      Wobenyzm N can be taken with a fish oil, prenatal vitamins, CoQ10, inositol, probiotics, magnesium citrate, Vit. D3,calcium and zinc. It will be best to discuss with your doctor the use of Wobenzym N with Prednisone, IVIG and Metformin as these are prescribed medications. Your doctor may approve, or help you transition, yet we are required to suggest you work with him/her to determine this.

      I wish you well!

  19. I’m almost 36 years old, I have one child she is 13 year old. Now we are trying to have another baby but it is being so difficult, I am wondering if we can get don natural help and see what happened before we decide to spend 20K for an IVF. Please let me know if you have any recommendation.

    • Hello Kary!

      I’m sorry to hear this, yet am thankful you reached out for support. We are more than happy to work with you! The very best way to receive a full plan designed specifically for your fertility health needs is to have a Fertility Consultation.

      Through a Fertility Consultation, you will submit your comprehensive intake form, including information about your fertility history, your 3 detailed questions and overall goal for your fertility and within 5 business days one of our Master Herbalists will review, layout and explain each step of your consultation. Once completed, your Fertility Consultation will be emailed to you as a PDF and you get a live link to an audio recording to save and review as often as you need. You also receive the opportunity to continue your relationship with your herbalist through follow-up email correspondence for a few weeks after receiving your consultation, with any questions you may have regarding your consultation.

      To learn more or book a Fertility Consultation click here…

  20. I had my tubes blocked by adiana 5 years ago and I’m wanting to conceive again. I’m just at a loss of what my options can be without spending 7,000 on a reversal and/or close to 10,000 for IVF. I’ve never had any infertility problems, that’s why when I was married I opted for the in-office procedure after our 3rd pregnancy. Now that I’m ready to conceive again with my new husband, of course, I’ve not been able to just “get pregnant” because they’re completely blocked(I had the dye test).

    • Dear Misty,

      I wish I could help you decide what to do. I thinks it’s going to be best to talk with your doctor about success rates/complications/all there is to know about tubal ligation reversal and then discuss the options with your husband. It’s such a personal choice for emotional and economic reasons.

  21. I can I still get rid of my ovarian cyst using the enzymes and DIM while on hormonal birth control?

    • Dear Rachel,

      We aren’t able to suggest combining Systemic Enzyme Therapy and Fertilica DIM Complete with birth control unless your healthcare provider supports and guides you in doing so.

  22. I have a thin uterus lining due to scarred tissue from c-sections will this help stregnthen my uterus again for more children? If so how soon could results be expected?

    • Dear Cameo,

      Systemic Enzyme Therapy is worth learning more about. It may also help to learn how to build it up the uterine lining naturally with a variety of natural therapies from our guide Thin Lining of the Uterus: Build the Uterine Lining Naturally.

      Truthfully, I can not know how long natural therapies will take for you. In general we suggest trying them consistently for at least 3 months time. Achieving fertility health is different for every couple dependent on diet, health history, stress levels, existing health conditions or imbalances, how well they stick to the program, and how severe the fertility issue is. If you are on one of our health programs, you should begin to see changes within 1-3 months. These changes could be increased energy, improved cervical mucous, ovulation, correction in cycle length, etc…

  23. Is it safe to take serapeptase and wobenzym during your period? Also, should castor oil packs be used at a specific time in your cycle?

    • Dear Kelly,

      Systemic enzymes can be used all cycle long with one exception. If menstruation is heavy, they should not be used until the period has stopped.

      Castor Oil Packs can be used from the day the period ends until ovulation when actively trying to conceive. If not actively trying to conceive they can be used after ovulation until the period starts again.

  24. Hello. Can I take Wobenzym with Vit C, Vit B, Magnesium, Zinc, Selenium, Calcium d-glucarate, Probiotics, and Apple cider vinegar(ACV helps my cramps a lot and it is full of enzymes)??

    Thank you. 🙂

    • Dear Sasa,

      All of those things can be combined that is fine. Apple cider vinegar contains many minerals and trace elements and some enzymes yet these enzymes are not digestive enzymes. If it helps with cramps, that is great!

  25. Can I use Wobenzym N during transfer or should I stop taking it right before my IVF transfer? Is it recommended for IVF? How should it be taken? Thanks

    • Dear Cam,

      This is a great conversation to have with your healthcare provider. We can not suggest its use without his/her approval and guidance in IVF. If you would like to use Wobenzym N into pregnancy (after transfer), please talk your doctor and considering sharing the study that proves its safety for use in pregnancy.

      My best!

  26. I have adenomyosis and extremely heavy periods. My cycle is usually 29-33days….my ovulation day varies. Adenomyosis was diagnosed after my third child and I have a new partner with no children and we are trying to conceive. There is almost 6 years since my last pregnancy and I am 32. Will systemic enzyme assist with fertility for me and help with my ehavy periods?

  27. I just ordered some and started taking yesterday. I missed a dose because I forgot about the empty stomach part. Is it ok to drink water, or does my stomach have to be empty of food and water? I am thinking of the 2 hours after lunch while I am waiting for my stomach to be empty so I can take my second dose.

    • Dear Kimberly,

      Systemic Enzyme blends can be taken with water. This is just fine! They are best taken 45minutes before a meal or 2 hours after. This is to prevent their breakdown in the stomach with digestion. Not to worry!

  28. I’ve had two chemical pregnancies (one in 2015 and another a week ago). it seems like I just start cramping and then its over. I have had an abortion in the past. I’ve also had a HSG to see if my tubes were fine which I was told they were. But I believe I may have scarring because I have a lot of discomfort on one side of my pelvic area. Do you believe wobenzym N can help? right now I have the following written down to purchase asap: Maca, rose hips, vitamin E, L-Arginine, Raspberry Leaf, and evening primrose.

    • Dear Ashley,

      I am so sorry!

      Well, your asking someone who feels most of us could benefit from enzymes and they have few contraindications, but I do think it would be best to first determine what this discomfort is caused by.

      You may appreciate also learning the causes of very early miscarriage, was well as how to keep moving forward with trying to conceive after a chemical pregnancy. We share all of this and more in our guide Chemical Pregnancy – Experiencing Very Early Miscarriage.

      Maca, Rose hips, vitamin E, L-Arginine, Red Raspberry Leaf, and Evening Primrose Oil all offer wonderful fertility health benefits.

      I hope this is helpful!

  29. hello
    after my 8 w pregnancy stopped developing i had undergone 1 aspiration and 2 w after 1 d&c and my ob says i have Asherman’s syndrome risk and prescripted birth control pills to restore my endometrium. would these enzymes help prevent Asherman’s syndrome? what dose? i am also taking aspirin to avoid clotting risk. thank you

  30. Hello, after reading many reviews I would like to know if Wobenzym can help. Last month I underwent Laparoscopy. My gyno found endo behind my uterus, my fellopians look like a string of sausages (thin thick think thick..) then he tried to perform hysteroscopy to remove polyp but he couldn’t get into the uterus due to scar tissue. I have never been pregnant and we have been trying for years only now with my new gyno we realised the issue(s). My periods are on time and I have no other symptom. Would Wobenzym help clear the tubes, and shrink scar tisue and endo? I am becoming so disappointed and hopless and would like to try it if somehow it helps. Thank you. I am 43 almost, ovulating still!

    • Dear Taline,

      Systemic Enzyme Therapy with Wobenzym N has many benefits as you have read. It could be considered as one part of a program to help the body relearn balance and maintain a healthy reproductive organ environment.

      Consider also learning the 5 Steps to Reversing Endometriosis Infertility and about Fertility Massage.

      We also offer this service, Fertility Consultations, that seems like it would be a really good fit for you. If you are interested, let me know and I will get you all the information about the program.

  31. Hi,
    We have been trying for the last year to have kids. I’m 43 and my fiance is 36. I was told my only hope was ZIFT as the fertility doctor discovered I have adenomyosis. Unfortunately the 5 zygotes we transferred into my fallopian tubes were not successful, the doctor told us this was our only chance of having kids. I have been onto your site a few times recently and wondering if taking Wobenzym n may heal my adenomyosis and improve our chance of having children. Any thoughts or suggestions would be appreciated.

  32. hi, ive had a hysterectomy and bowel resection due to endo, i also have thyroid problem. will this treatment work for me as im still having endo pain and scar tissue.

    • Dear Nichola,

      It may be worth learning more about and considering. One does not need a uterus in order to use systemic enzymes. They work throughout the body where there is need.

      Consider also learning about the herb Black Cohosh. It is widely used because it is an excellent anti-inflammatory herb and heart tonic. We share more about Black Cohosh here…

      I hope you find some things to help!

  33. I did lots of scan and ultrasound and my obgyn said it was uterine fibroids. I was scheduled for a surgery. Then when the doctor reviewed my MRI photo he said I had adenomyosis instead of fibroid. I want to have more kids. What therapy is good for me please?

  34. Hi, I just had a hysteroscopy for asherman syndrome. what do you recommend to help lower the chance of scar tissue from reforming?

  35. Hi, I recently had experienced an ectopic pregnancy and today I have found out that I do have severe endometriosis.

    I want to start the fertility cleansing kit and Wobenzym N. Can I take Wobenzym N while I am on the fertility cleansing? I also have purchased vitex, dim, mama, and royal jelly capsule from your site. Can I take them while I am on fertility cleansing?

    Do you have any success stories women with endometriosis?

    • Dear Min C,

      I am very sorry for all you are going through!

      In general, we suggest starting with the Fertility Cleanse and completing that before starting to many other new supplements. That said, Wobenzym N, Maca, Royal Jelly and DIM can all be combined with the cleanse and then continued after. It is best to wait to begin Vitex until cleansing is complete. If taking all of these things together seems overwhelming, it is fine to cleanse and then begin the other supplements after.

      We share success stories of women with endometriosis here…. I hope this is helpful and know that we are here to offer support if you need.

  36. Wobenzym N was recommended by my acupuncturist. I am going to be going through IVF. There are a few different dosages. You had written that you recommend taking 3 tablets 2 times daily. What dosage of tablets would you recommend in my case?

    • Hello Rebecca K!

      Consider asking your acupuncturist as well. We are only able to share general suggested use which is as follows:
      – As a dietary supplement – Adults take three (3) tablets, twice daily, on an empty stomach at least 45 minutes before meals with water.
      – Advanced Usage: Adults may gradually increase to 12 per day by taking 3 tablets 4 times per day on an empty stomach.

      Our IVF Checkliste may be helpful as well.

      Best wishes!

  37. What about the reported risk of surges in Oestrogen from taking systemic enzymes? Thanks again

    • Dear Vanessa,

      It has not been our experience that Wobenzym N causes oestrogen surges. I’m not sure the validity of said reports. I have not seen them.

  38. Hi, is it best to take away from menstruation? I have read it is a blood thinner and for those with heavy bleed and anaemia can make the bleed worse? I also read that Vitalzyme with serrapeptase is better for fibroid shrinkage? What do you think? thanks v much

    • Dear Vanessa,

      Yes, those with heavy menstrual bleeding would not want to take Wobenzym N while menstruating. While others may have had success with other enzymes/enzyme blends, Wobenzym N has been studied for fertility and in pregnancy making it our go-to fertility enzyme blend.

  39. Is it OK to take both Wobenzym N and L-Arganine at the same time? Thanks!

  40. I have just had a procedure to remove a polyp in my uterus, am I OK to start using Wobenzym N 200? I suffer from blood stagnation and endometriosis and also have blocked tubes due to endometrial scarring and thought I’d give Wobenzym a go to alleviate pain and possibly help me to conceive.

  41. Can wobenzyme N be combined with serrapeptase? Do you also have a natural supplement you would recommend for hypothyroidism. I am doing everything I can to chance my diet and decrease environmental toxins. I really do not want to start taking thyroid meds ( was just diagnosed but haven’t agreed to prescription meds) if I can do it naturally. I also don’t want to mess around and miss being able to conceive and carry to term.
    I just checked enzymedica and they have many products. Which one would be similar wobenzyme? I haven’t tried wobenzyme yet, just asking. I am waiting for your response on my hypothyroidism question. Thank you. Many blessings.

  42. Can I take Wobenzym at the same time as I am taking Women’s Best Friend or do they have the same compositions?

  43. I have to take Armour Thryoid medicine in the morning. Can I take Wobenzym at the same time or will it affect my thyroid medicine?

    • Dear Elizabeth,

      It will be best to discuss with your doctor or pharmacist the possibility of combining Wobenzym N with your thyroid medication. He/she is best able to help you maintain the proper dose of medication for your needs should you choose to take them both. If you choose to take them both, it may be best to take them apart from one another.

  44. I have unexplained infertility possibly caused by poor egg quality, plus i have immune issues (inflammation). Could i take Wobenzym with dong qua & chaste berry? Thanks.