How to Use Systemic Enzyme Therapy to Increase Your Fertility…

How to Use Systemic Enzyme Therapy to Increase Your Fertility…

What are Enzymes?

Occurring in every living thing on earth, enzymes are biological molecules that catalyze (increase the rate of) chemical reactions. Almost all chemical reactions in the cell need enzymes in order to occur at rates sufficient for life. They build new proteins, cells, tissues and organs, and also tear down these same tissues.

The ability to ward off disease, repair injuries and sustain the body’s homeostasis are all connected to the concentration and strength of enzymes we have in our bodies. There are over 3,000 different types of enzymes in the human body constantly at work initiating millions of chemical reactions every second in the human body. If we did not have enzymes there would be no digestion, no blood coagulation, no reproduction, no breathing and no use of the senses. This gives you an idea of how important enzymes are for the body.

In the body there are many different types of enzymes. We have all heard about digestive enzymes, which help us to digest our food, but there are enzymes that help with all the other functions of the body as well, these are called systemic enzymes. Systemic enzymes work on the entire system.

Benefits of Systemic Enzymes

Systemic enzymes have been studied and shown to provide many benefits beneficial for healthy fertility.

Some of the beneficial actions systemic enzymes have within the body are to counteract chronic inflammation, reduce the substances in the blood that trigger an hyper-autoimmune response, break down fibrin (the substance that scars are made from) and improve blood flexibility and flow. All of these actions can help to support healthy reproductive function.

Anti-Inflammatory Effect
Systemic enzymes help to break down the substances in the blood that create inflammation and infection. This may benefit those experiencing inflammation from endometriosis by reducing the inflammation caused from the scar tissue irritating the surrounding organs and may help with the pain that sometimes comes from having endometriosis.

Regulatory Effect on the Immune System
Systemic enzymes help support the body to reduce a hyper-immune response in the body. One study has shown that they may help to prevent the rejection of the fetus (recurrent miscarriage) and help with other issues related to reproductive immunological imbalances.

Systemic enzymes have also shown to benefit autoimmune hypothyroidism – Hashimoto’s. One study noted that taking Wobenzym resulted in a reduction of autoimmune antibodies that attack the thyroid. Hypothyroidism can be a cause of infertility or recurrent miscarriages.

Breaks Down Scar Tissue
Some systemic enzymes have the ability to break down fibrin, the substance that makes up scar tissue. Scar tissue and adhesion causing fertility issues can form for a variety of reasons including uterine fibroids, pelvic surgery such as Cesarean Section, PID, damage to fallopian tubes, ovarian cysts, endometriosis, IUD, or abortion.

How systemic enzyme blends eliminate scar tissue:

  • The systemic enzyme blend works as a biological response modifier; working with the bodies own immune defense system to moderate inflammatory response.
  • They support cleansing of the tissues, promote better circulation.
  • They break down and remove “fibrin”, the make-up of prolonged inflammation and scar tissue/adhesion formation.
  • They break down the proteins in the blood that cause inflammation, this facilitates their removal via the lymphatic and circulatory system.
  • Reduction in inflammation , increase in proper blood formation, increase in proper circulation hinders scar tissue and adhesion formation, while reducing pain.

Improves Blood Flow

Systemic enzymes cleanse the blood, promotes circulation an stimulates the formation of new, healthy tissue.

Proteolytic enzymes improve blood flow by increasing the flexibility of red blood cells, inhibiting the aggregation of platelets, and helps to prevent abnormal blood clotting. Systemic enzymes also help to support the cleansing of the tissues and promotes better circulation as well as stimulating formation of new, healthy tissue. Simplified they make the blood less “sticky”. This is beneficial for reproductive health in many ways.

The blood cleansing actions of systemic enzymes help to bring proper circulation to the reproductive system and get the “stagnant blood” cleared out helping to remove toxins and also bringing fresh oxygenated blood to your uterus, ovaries and eggs. Imbalances which are considered stagnant are endometriosis, PCOS, heavy dark menses, ovarian cysts and uterine cysts. The fresh oxygenated, free flowing blood is also able to transport more nutrients to the eggs, supporting egg health.

Types of Systemic Enzymes and Their Actions:

The benefits mentioned above have been validated through studies done over the last 40 years on an enzyme blend containing these specific enzymes:

  • Bromealin: Breaks down protein and is a beneficial as an anti-inflammatory.
  • Chymotrypsin: Breaks down proteins, primary anti-fibroid enzyme and has a beneficial effect on the blood. It also works as a catalyst joining the actions of all the enzymes in the blend.
  • Pancreatin: A combination of pancreatic enzymes secreted by the pancreas. Made up of amylase, lipase and protease. These enzymes help to break down carbohydrates, regulates histamine, breaks down fats, helps reduce cholesterol, supports hormone production, bonds with alpha 2-macro-globulin to support immune function, reduces inflammation and increases circulation.
  • Papain: Extracted from papaya, papain breaks down protein and is most beneficial as an anti-inflammatory.
  • Rutin: Breaks down protein and is as beneficial as an anti-inflammatory.
  • Trypsin: breaks down proteins and can have beneficial effects on the blood, such as reducing the risk of blood clots.

Systemic Enzyme Therapy for Fertility

Systemic Enzyme Therapy is a natural method utilizing these unique enzymes to help support reproductive health and fertility. There are many fertility issues that may be supported with the use of systemic enzymes. Plan on using them for at least 3 months or more before you begin trying to get pregnant, depending on how long the issues has been around. Here are some of the issues systemic enzymes may help with:

Systemic Enzyme Therapy is one of the best and most effective natural therapies for endometriosis. Systemic enzymes may help to reduce the scar tissue and breakdown the excess tissues left from endometriosis.

Systemic Enzyme Therapy may also aid women who have endometriosis by reducing the inflammation caused from the scar tissue irritating the surrounding organs and may help with the pain that sometimes comes from having endometriosis.

The blood cleansing actions of this therapy help to bring proper circulation to the reproductive system and get the “stagnant blood” cleared out, bringing fresh oxygenated blood to your uterus and ovaries.

For this purpose it is best to start the Systemic Enzyme Therapy with The Fertility Cleanse. For endometriosis it is suggested to stay on the Systemic Enzyme Therapy for at least three months prior to trying to get pregnant so all of the stagnant tissues and scar tissues can be cleared.

Recurrent Miscarriage
For recurrent pregnancy losses caused from either immunological response or blood clotting, Systemic Enzyme Therapy is an affective option. In a five year study women who had experienced a recurrent miscarriage due to immunological response (more than 30% of miscarriages) were put on a systemic enzyme supplement before and during there pregnancies(1). 79% of the women carried out their pregnancies to term and gave birth to healthy babies. This is an amazing discovery. The only options available before this study were anti-immunological agents similar to the type used in transplant patients, but most doctors will not use them due to there toxicity during pregnancy.

The best product we have found and the product that was actually used in the study mentioned above is Wobenzym N. It is the only systemic enzyme product that has been studied and used during pregnancy. You can also use this study if you would like to talk to your doctor about using this product during pregnancy.

Uterine Fibroids and Cysts
The systemic enzymes have been shown in research to reduce the engorgement (swelling and pain) of fibrocystic conditions. They also eat away at the cysts reducing their size or eliminating them over time. With uterine fibroids it is important to also make sure you are reducing your estrogen exposure and actively getting rid of excess estrogens, this can be done with the estrogen metabolizer DIM.

Using Systemic Enzyme Therapy is one of the two most important natural therapies for uterine fibroids. I have not found a more powerful way of reducing or supporting the body in eliminating uterine fibroids.

Old Scar Tissue and Blocked Fallopian Tubes
Systemic Enzyme Therapy can help to reduce the scar tissues left from surgeries like cesareans, PID, tubal reversal, abdominal surgery, etc. which may be affecting your reproductive system. Specific systemic eat away and reduces the fibrin (the material that makes up scar tissue) over time. This therapy is extremely effective at reducing scar tissues.

Scar tissue and adhesion causing fertility issues can form for a variety of reasons: uterine fibroids, pelvic surgery such as Cesarean Section, PID, damage to fallopian tubes, ovarian cysts, endometriosis, IUD, or abortion.

Pelvic Inflammatory Disease
A systemic enzyme blend was studied and found to be as effective as medication at helping the body to overcome Pelvic Inflammatory Disease (PID). PID is a general term used to describe inflammation of the uterus, ovaries, and/or fallopian tubes. PID can be cuased by parasitic, viral, fungal, but most often through bacterial infection. If left untreated PID can lead to scar tissue and adhesion formation. If PID advances to this stage it may lead to blocked fallopian tubes and sterility in women. PID often comes from Sexually Transmitted Disease (STD’s). 2/3 of women who have undergone laparascopic surgery to determine infertility cause who were found to have PID were unaware they even had PID.

A randomized double-blind study was performed on 100 women with Pelvic Inflammatory Disease. One group was given 5 tablets of Wobenzym N, three times a day. The control group was given an NSAID drug in the usual dosage. Both groups were also given antibiotics (PID requires antibiotics). The patients were given the treatment for 16 or 17 days. Wobenzym N performed with amazing results in fighting damage to tissues, pain, inflammation and overall pelvic congestion. 57% of women using Wobenzyme N were without any complaints, whereas only 6% of women who took NSAIDs were without complaints. Overall, 100% of the the patients who use Wobenzyme N reported their condition as substantially improved, compared to only 73.5 % using the NSAIDs. In addition studies have shown Wobenzym N enhances the body’s response to use of antibiotic medications.

Supporting Egg Health
One of the major factors for increasing egg health is to increase the circulation to the ovaries. Systemic Enzyme Therapy can help to cleanse the blood, increase circulation and make the blood less “sticky”. For best results use the Systemic Enzyme Therapy in conjunction with the OvaWise Health Program.

How to Use Systemic Enzymes

For the best results you must take a high quality systemic enzyme that contains the specific enzymes listed in the ‘Types of Enzymes’ list. The one we feel is the best is the enzyme blend that was used in the studies mentioned through out this guide and has been studied and used for over 40 years – Wobenzym N.

“Wobenzym N is the most thoroughly researched enzyme mixture available worldwide. Wobenzym N contains five potent enzymes including pancreatin, trypsin, chymotrypsin, bromelain, and papain, as well as the bioflavanoind rutin. Wobenzym is clearly the most scientifically and clinically validated enzyme formula in the world.” -Michael Loes, M.D., M.D. (H.)

Wobenzym N combines all the beneficial delicate enzymes and is protected by a vegetable-based enteric coating which ensures optimal absorption and utilization in the blood stream.

Suggested Usage: Adults take three (3) tablets, twice daily, on an empty stomach, with water at least 45 minutes before meals and 2 hours after eating to take your enzymes.

Advanced usage: Adults may gradually increase to 12 per day by taking 3 tablets 4 times per day on an empty stomach.

Take on an empty stomach: This is very important. The enzymes need to make it past the stomach to be absorbed in the intestine. Do not take with food. Wait at least 45 minutes before eating and 2 hours after eating to take your enzymes.

Safety & Side Effects

There has been no toxicity shown from using systemic enzymes. There is no dangerous or lethal dose of systemic enzymes. These enzymes are the same enzymes the body naturally contains. Wobenzym can be used in preconception and has been shown to be helpful throughout pregnancy (see above information) with the agreement/approval of your doctor.

Stop taking systemic enzymes two weeks prior to any type of surgery. Use systemic enzymes in preparation for conception, not while you are pregnant or may be pregnant. If you are using Wobenzym for possible miscarriage prevention, please talk with your doctor and get their approval for use during pregnancy.

Use During Pregnancy

Wobenzym can be used in preconception and has been shown to be helpful throughout pregnancy to help prevent recurrent miscarriage due to immunological imbalances (see study under Recurrent Miscarriage section) with the agreement/approval of your doctor. Please consult with your doctor or midwife before using any supplements during pregnancy.

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  1. Hi, I am 39, had 2 caesarian section and currently trying for a third baby and I had ectopic pregnancy in July 2014. I also had cysts in my left ovary since 2011. In my recent ultrasound, scar was found in the left ovary because of the ectopic pregnancy. I want to have another baby. Please advise which programme should I take? Thanks

  2. Hi! I’ll be taking Prednisone to suppress my immune system for IVF and was wondering if I can take Wobenzym N as well? Many thanks.

    • Dear Nina,

      Because you are currently already on Prednisone and undergoing a procedure you should not combine herbs or some nutritional supplements with your medications. Consider speaking with your reproductive endocrinologist if you are still considering it.

      Best wishes for great success!

  3. Hi im starting IVF this month and have ben told I have elevated natural killer cells which is an immune problem. I was wondering if I can start using wobenzym n during my treatment or have i left it to late? If i can how long would i need to take it for? I also have an underactive thyroid. Would it be safe to take wobenzym alongside my thyroid medication. Thanks.

    • Dear Nina,

      It will be best for you to consult your healthcare provider about taking Wobenzym N during your treatment, as well as to discuss proper dose for your needs and the duration of time it can be taken. He/she can also guide you in using it with your medications if they feel you can.

      Best wishes to you!

  4. I am iron and b-12 deficient. I take both as supplements daily. Can Wobenzym be used safely with these deficiencies and supplements? Thanks for your input.

    • Hello Erica!

      It may be best to speak with your healthcare provider about taking Wobenzym N.

      Wobenzym N can be combined with iron and vitamin B12 supplements.

  5. Hi! I have had PID for 9 years now. For two weeks I have been on systematic enzymes and have been taking lecithin and DIM for a month now. My husband and I are trying to conceive. What will be the best options?

    • Hello Brittany!

      I am sorry you are having to deal with PID.

      Systemic Enzyme Therapy has been shown to benefit those with PID and I would encourage you to learn more about studies in the article How to Use Systemic Enzyme Therapy to Increase Your Fertility… There are also advanced use instructions that may be worth considering.

      Supporting the body in dealing with the inflammation PID often promotes is going to be key as well. An anti-inflammatory Fertility diet that includes foods like wild Alaskan salmon, healthy fats and omega 3s like Cod Liver Oil, avocado, nuts and seeds, spices like turmeric, ginger, cinnamon and garlic, Asian mushrooms, whole grain, beans and legumes, whole vegetables and fruits, even plain dark chocolate, should be considered. Foods to be limited are fatty, non-organic red meat, dairy (although quality hard cheeses and yogurt is okay in moderation), white refined grains and white rice, a diet high is sugar and artificial sweeteners, coffee/caffeine and soy. Is your lecithin supplement from a soy source? It may be worth considering changing to a non-soy sourced lecithin if you feel this is an important supplement for you.

      I hope this is helpful!

  6. Hi! I have had 3 miscarriages in the last year and believe I have had subsequent early miscarriages, but cannot prove this as I am not getting a positive test. I am very fertile, but convinced it is an immune problem (rejecting the embryos although not tested for this yet). I have had other tests that have come back clear. I have been taking Wobenzym N, 3 tablets, twice daily on empty stomach for 1 cycle now, but don’t think it has worked this time. I am still following my usual cycle of spotting from day 18 of cycle. It says you can gradually increase the dosage. How would you recommend to increase this? 3 x day next cycle or can I go straight to 4 x day? Thanks for your help!

    • Hello Jenny!

      I am sorry for your losses and that you have yet to learn why this is happening.

      Do you have other immune system issues or illnesses that have led you to believe Immunological Infertility is a factor for you? There are many links between hormonal imbalances, even dysfunction of the uterus which may cause implantation problems, and recurrent miscarriage. These in addition to stress, work-life balance, diet, exercise, etc. can all have an impact on not only one’s ability to conceive, but sustaining pregnancy as well.

      Advanced use of Wobenzym N for adults is to gradually increase to 12 tablets per day by taking 3 tablets four times per day on an empty stomach. One way to do this is to take 3 tablets three times a day for the next cycle and then the following cycle increase to 3 tablets four times per day.

      I hope you are able to seek testing to help you understand exactly what you may be causing you to miscarry. This should provide information that will be helpful in creating the best program for your needs.

      Take care!

    • Hi Elizabeth

      Thanks for responding and for your advice. I don’t have any specific immune system issues, in fact my immune system has always been very good. However, I do suffer with IBS which only tends to flare up when I’m fighting infection, it’s been flaring up every month about a week after ovulation.. with usual IBS stomach pain causing bloating, excess gas and trapped wind pain. I thought it was worth a try whilst waiting for a referral to St Marys London.

      Although I have read today about soya milk, and it’s bad for fertility. I’m dairy intolerant and substitute milk for soya! Will stop straight away. Otherwise I eat a very healthy diet, and exercise regularly. Jenny

    • Hi Jenny!

      You are welcome! I am sorry you have to deal with IBS.

      Consider also learning about Licorice Root and its emollient, demulcent and nutritive properties.

      Nut milks like almond and help milk may be substitutes for dairy and soy milk and worth considering.

      Take care!

  7. Hi. Unfortunately, I have contracted an STD on several occasions in the past. Most were treated quickly. There was one occurence of PID. This has caused scar tissue to form. I am not sure of the extent of the scar tissue but in 2013 I attempted to have an IUD inserted and it could not be done due to the scar tissue. Although I am not actively trying to conceive at the moment I am researching the effects this will have on my fertility.

    Could Wobenzym N help me? How long does it take to have an effect on scar tissue? And although I see that it is okay for long term use, if you stop taking it does the scar tissue reform? (I read that scar tissue can reform when removed surgically)

    • Dear Jessica,

      One of Wobenzym N’s primary fertility benefits is to support the body’s ability to break down fibrin (the substance that makes up scar tissue). There is a doctor who has studied how Wobenzym N may relieve the symptoms of PID which you can learn more about here…

      Wobenzym is best used for 1-3 months consistently for most conditions. I can not know how long it will take you to see results. Each person responds so differently an likewise experiences a fertility issue so differently that it is hard for me to know.

      The way in which systemic enzymes work is to help the body realize it can function in a certain way on it’s own, in cases like this that the body can manage scar tissue growth on its own. Again due to the aforementioned factors, it is hard to know if every body that is offered systemic enzyme support will be able to manage scar tissue growth completely on its own.

      I hope this is helpful!

  8. Hi there,
    I have been diagnosed with a fibroid cyst in my uterus, 2 blocked tubes and natural killer cells. I have tried everything from gf diet to accupunture over the last 7 years to get pregnant, we have done ivf and ICSI during this time as well, can you pleeeeease suggest anything

    • Elizabeth Willett, MA, CH

      Dear Charlie,

      I am sorry you have been faced with these challenges!

      Given the amount of time you have spent on healing and the number of therapies you have tried, the very best way for us to guide you is through a Fertility Consultation. During a Fertility Consultation, our fertility herbalist is able to work with you one on one and to consider your detailed health history including all that you have tried to support your fertility health, your diet, lifesytle, and stress levels when creating a Natural Fertility Program for your specific needs.

      I hope you will consider this personalized guidance!

  9. I have been using Wobenzym N for 2 months now – I started in September with the fertility cleanse. We just did a FET a week ago and I am pregnant. I have endometriosis, and I did IV intralipids this month because of 2 early losses this past year. How long should I keep taking Wobenzym N?
    Thank you!

    • Elizabeth Willett, MA, CH

      Dear Michele,


      According to German research, Wobenzym N has been shown safe for long term use, even in pregnancy, under the supervision of your doctor. I hope your doctor is aware you are taking Wobenzym N and can guide you in continuing to take or discontinuing it. He/she knows your needs best! Please consult him/her.

      Best wishes!

  10. Hi
    I have adenomyosis which I believe is causing extreme bladder discomfort and pressure with the need to constantly urinate (I have had urine test-no infection). Could the systemic enzyme therapy help relieve this? Any other suggestions are very welcome.

    • Elizabeth Willett, MA, CH

      Dear Jules,

      I am sorry you are having to deal with this. Don’t hesitate to contact your healthcare provider if your discomfort it disrupting your lifestyle or causing you pain.

      Systemic Enzyme Therapy uses systemic enzymes that have been shown to work to reduce pain, inflammation, and prevent scar tissue damage. Consider additional ways you can support uterine health through the article Adenomyosis: Causes, Risks, & Natural Healing Options.

      Take care!

  11. I had an endometrial ablation (Novasure) in 2012 for heavy periods. At that time I was married and we had 5 kids between the 2 of us. I was told it wasn’t BC, but my husband had a vasectomy, so I wasn’t concerned. A few weeks after the procedure I found out he had been having multiple affairs, and here I am a newlywed again, wanting another child. I have been having normal periods for about 1.5 years now (the procedure never really worked and my periods never fully stopped) and I know it is possible to get pregnant after it, even though risky. I’ve been drinking Raspberry leaf tea but I’m not sure what else I can do to heal my uterus. Any thoughts?

  12. Interesting article and I just bought Wobenzym N. In 2009 I had an appendectomy and a month later I had an ectopic pregnancy… We think due to the appendicitis. In 2011, I had a successful pregnancy. Prior to this pregnancy I did have a hysteriosalpingogram. As of October 2014, I had another ectopic pregnancy on the side of the abdominal surgery. Besides taking Wobenzym N, what other holistic approaches do you recommend to ward off ectopic pregnancies in the future. There’s not much information on this out there and any advice would be awesome! THANKS!

    • Elizabeth Willett, MA, CH

      Dear Kate,

      Our senior herbalist wrote a detailed article titled Healing From Ectopic Pregnancy that offers guidance for supporting normal fallopian tube function, by supporting the body’s natural inflammation and immune response, encourage healthy circulation to the fallopian tubes and reproductive system, all while promoting the body’s natural ability to cleanse the reproductive system in part by aiding the breakdown of fibrin (bands of scar-like tissue).

      Best wishes to you!

  13. I have had an ectopic in July, and was lucky to keep my tube after taking MTX shot. In saying that I have concerns for falling pregnant again because whatever side it occurred on will be damaged from the trauma and am scared to go through this all over again &end in a rupture next time maybe? What’s more confusing is I even did an HSG so the ectopic doesn’t add up?

    I have read some articles on your site &I was wanting some advice of where to start as I want to reverse any scar tissue or at least create a better environment for when I may be ready to fall pregnant. I also have a history of ovarian cysts and have hashimotos. But where to start? Fertility cleanse, wobenzyme, massage, etc

    • Elizabeth Willett, MA, CH

      Dear Faith,

      I am sorry you have had to go through this!

      Consider learning how to naturally support fallopian tube health after ectopic pregnancy.

      We do consider Fertility Cleansing a great way for anyone who is experiencing fertility challenges to create a foundation for hormonal balance and a healthy reproductive system after which one can naturally support their specific fertility issue.

      You may also want to consider a Fertility Consultation. Our email Fertility Consultations provide you with a personalized written guide and audio recording from our fertility herbalist, explaining the best natural therapies, herbs and nutritional supplements for your unique fertility issues.

      Best wishes!

  14. Can this treatment help with cervical hostility?

    • Elizabeth Willett, MA, CH

      Dear Jo,

      Systemic Enzyme Therapy may be considered in some cases where there is an immunological attack on the sperm. I am not sure about the reasearch on systemic enzymes helping a woman’s cervix not react to sperm. Consider learning more about Cervical Hostility and Regaining Fertility to Get Pregnant as you educate yourself.

      I hope this is helpful!

  15. I have a complex ovarian cyst that is about 4 1/2 cm. We are going to wait it out and see if it resolves on its own. I will have a follow-up ultrasound in 6 weeks. My doctor offered me a progesterone only bc pill to help shrink it, but I do not want to go that route. I would love to try the enzymatic route to see if it will help resolve this for me.

  16. I just had a ruptured tube as a result of ectopic pregnancy, was taken in for urgent surgery. still would like to have another child but am confused about conflicting advise of two doctors. one suggested to wait for at least 3 months before getting pregnant while the other said there is no need to wait but should immediately report to the clinic if i missed my period. the operated surgery did not give sign of ectopic pregnancy ‘cos i was seeing my period normally during the whole time. what do you think i should do?, waiting for 3 months is not a problem but i also learn’t that using contraceptive may hinder quick conception, is this true? which of the advise should i adhere to?

    • Elizabeth Willett, MA, CH

      Dear Esther,

      Contraceptives, in the form of hormonal birth control, is designed to stop your body from ovulating to prevent pregnancy. It is ultimately up to you how long you wait to try to conceive. Did either doctor share with you why they suggested you wait or not? If you wish to wait three months to try to conceive, you can still have intercourse. Is this a concern for you? You can either use contraception like a condom during this time, or learn about the Fertility Awareness Method to know your most fertile days each cycle and avoid intercourse during these days.

      I hope this is helpful!

  17. hi, i’m suffering from two blocked fallopian tubes.. will Wobenzym N help me to open up the blockage & possibly get pregnant? i’ve been trying for the past 7yrs & i’m not getting any younger.. can you also suggest any other natural remedies for me to get pregnant asap? if ever can you also help me find a way to order Wobenzym N since i’m from asia? thank you

    • Elizabeth Willett, MA, CH

      Dear Macy,

      Thank you for reaching out to us.

      Wobenzym N is the product used in Systemic Enzyme Therapy which has been shown to have a number of benefits for reproductive system health. You are welcome to order Wobenzym N from The Natural Fertility Shop and please contact customer care with additional questions about ordering.

      It is important to recognize that each fallopian tube is about the size of a spaghetti noodle in width and is very delicate. We have learned that any sort of trauma can damage tubal tissues and alter fallopian tube function. Once they are damaged it may be difficult to reverse that damage.

      While we feel Systemic Enzyme Therapy using Wobenzym N an important part of supporting normal fallopian tube function, fallopian tubes that are severely damaged need special care. We suggest you work with a specialist who will be able to evaluate your unique situation and determine the best possible course of care.

      The good news is that natural therapies can be used alone, or alongside any type of treatment options you are considering, which may greatly help to improve outcome.

      Please take some time to read the article that our founder wrote about supporting fallopian tube health to learn more.

      Best wishes!

  18. hi! I already had surgery last year to remove cysts but they are back and i have endemetriosis on my left (4cm) and right (10cm) ovary. is there still a chance to reduce their size?

    • Elizabeth Willett, MA, CH

      Dear Dessa,

      I am sorry you are having to go through this! Unfortunately many women have surgery only to experience their issues again. While surgery in necessary for some, it doesn’t have the capability to address the underlying imbalance that is contributing to many hormonal issues.

      There are ways to naturally support the body in finding balance and in doing so you may in part support the body’s natural ability to remove excess estrogen from the body, help to maintain the body’s natural inflammatory response and aid the body’s natural ability to break down fibrin (tissue that makes up a scar tissue). Learn more about supporting hormonal balance when excess estrogen may be a culprit here…

      Take care!

  19. Hi, I was wondering if I can do systemic enzyme therapy (take Wobenzym) while doing a fertility cleanse?

    • Elizabeth Willett, MA, CH

      Hello Nancy!

      Yes, you can take Wobenzym N while doing the Fertility Cleanse. Wobenzym N can be taken all cycle long unless you have heavy menstrual bleeding in which case it should be avoided during menstruation.

      Be well!

  20. Dear Elizabeth,

    I have recently been diagnosed with having 2 ovarian cysts (each about 4cm and 5 cm). And currently i am suffering from hypothydrodism. My gynae has put me on 3 months contraceptive pills to monitor the cysts. As such, i am wondering during this period would it be advisable for me to take Wobenzym?

    Would appreciate your advice greatly.

    Thanks you,

    • Elizabeth Willett, MA, CH

      Hello FL!

      Wobenzym N can be taken with contraceptive pills, but it is always best to discuss all that you are taking and doing to support your fertility/fertility issue with your healthcare provider. While Wobenzym N is part of the ovarian health program it is best to use the entire program. You can learn more about supporting ovarian health here…

      You might also like to read for additional guidance.

      I wish you well!

  21. Dear Elizabeth,

    Is it proven that Wobenzym N can actually break down existing adhesions and are already formed?

    Also I have just started taking a daily does of Vitamin E, vitamin B complete, Iron, Shatavari power, and respberry leaf tea. In to hope of rebuilding my uterine lining. Would it be too much to take the Wobenyzme N on top? is it all to much for my body to break down?

    Kind regards


    • Elizabeth Willett, MA, CH

      Hello again Lisa!

      Years of scientific research has shown Wobenzym N efficient in supporting a number of fertility issues. Please take a bit of time to read at length about this research and the Fertility Benefits of Wobenzym N here…

      Wobenzym N can be combined with Vitamin E, a Vitamin B complex, Iron, Shatavari and Red Raspberry Leaf tea without concern.

      In health ~ Liz

  22. Hi Dalene and Elizabeth.

    I have recently been diagnosed with adhesions in my uterus and 4 mm endometrium after a d&c. I have been suffering for severe pain during ovulation and during period. I am suffering from pain in my uterus and ovaries. Can you recommend a blend of Systemic Enzyme Therapy that will help break down adhesions and help rebuild the lining of my uterus.

    Thank you kindly

    • Elizabeth Willett, MA, CH

      Dear Lisa,

      The product we support for use in Systemic Enzyme Therapy for fertility is Wobenzym N. Wobenzym N in part support the body’s ability to break down fibrin (the substance that makes up scar tissue), encourages normal circulation to the reproductive system, which in turn supports a healthy vibrant uterus and uterine lining, and supports the body’s natural inflammation response, providing relief for occasional discomfort in the reproductive system.

      Take time to also learn additional ways to build the uterine lining naturally.

      You might also appreciate Women’s Best Friend Lisa. This herbal combination supplement combines herbs to reduce occasional discomfort and swelling of the female reproductive system.

      Take care!

  23. I am a 50year old woman., I have been recently tested for fibroids in my uterus (3)and my left fullopian tube is swollen shut and my left ovarie is closed also has (2) cys mass on it 1- is 5.8cm,and 1- is 4.0cm and I don’t have a right Fallopian tub it was removed 5yrs a go, but I have my right ovarie but it is closed they want to do a total hysterectomy,is there anything I can take that will prevent this from happying. Thank you for your time,. -teresa

  24. Hello

    I’m 43 years old had multiple miscarriages which lead to me having to undergo three operations 2 myomectomies in 1999 and 2012 and one UAE (Embolization) in 2009. I recently did an HSG to see my tubes are block since I was not getting pregnant, the findings of the HSG is that the ” uterine cavity is not well outlined with concern for synechiae. Contrast spillage into the peritoneum is evident denoting patency” i then had uterine evaluation by Hysteroscopy the findings are fixed atrophic uterus – Ashermans. An ultraSound show there is marked UAE effect and dense fibrotic rings around the endo/myo junction. Can I try enzyme therapy my only option is surrogacy and we do not want to go

    • Elizabeth Willett, MA, CH

      Hi Brenda!
      I am sorry you have had to go through all of this!

      Systemic Enzyme Therapy has been shown to be supportive in part in certain cases of the body’s ability to break down fibrin (the substance that makes up scar tissue), normal circulation to the reproductive system, aiding the body’s natural ability to reduce tissue buildup in the uterus and the body’s natural inflammation response, providing relief for occasional discomfort in the reproductive system.

      Fallopian tubes and a uterus that are severely damaged need special care. In those cases we would suggest you work with a specialist. A specialist will be able to evaluate your unique situation and determine the best possible course of care. Clear Passage Physical Therapy Clinics may be one option.

      The good news is that natural therapies can be used alone, or alongside any type of treatment options you may consider, which may greatly help to improve outcome.

      I wish you well!

  25. how long do you take the wobenzym n and I read something about not taking when menstruating..please advise.

    • Hi Shandrea,

      Wobenzym N used as systemic enzyme therapy is best avoided during menstruation by women with heavy menstrual cycles. Wobenzym N has a slight blood thinning action, which may potentially cause heavier menstrual bleeding.

      Wobenzym N is best used therapeutically for at least 3-6 months consistently, or as directed by your healthcare provider.

      All the best!

  26. I have Ashermans syndrome and would like to try enzyme therapy. Can I take Wobenzym N while doing the fertility cleanse or is it best to do the cleanse first?

    • Hi kristie,

      Wobenzym N is fine to combine with the Fertility Cleanse Kit products. Let us know how it works for you and thank you for contacting us!

  27. Hello

    I have many ovarian cyst and they are 10cm in diameter. I have hypothyroism and are now having a big hormon/liver and gallbladerdetoxs and are also trying to get my metabolism in order with mineralterapi. I dont know what kind of cyst i do have. You named tre types that maybee doesent answer to your treatment, should I Be worried? My doc were very arogant and wanted to surgey them out, but I dont trust these doctors with knives. Can you tell me about your experients of cyst in this sizes?? I love your site! Thank your for everything, this is giving my hope!

    • Hi Elisabeth,

      You said that you have many ovarian cysts that are all 10cm? 10cm is quite large for one ovarian cysts alone, but to have many that size threatens permanent damage or even the loss of the ovary. If you are uncomfortable with your doctor, you may want to seek a second opinion. At the very least, I encourage you to open a line of communication with your doctor or his lead nurse, so you can find out what type of cysts you have and what the risks are to your health to not have surgery performed. It is true that complex cysts, as some are named in this article, often don’t respond to the natural therapies listed in this article as well as functional ovarian cysts do. This is why it is important to find out the type of cysts you have.

      I hope this helps you to make a decision. Be well :)

  28. Hello, I would like to avoid surgery to remove fibriods for a second time and I would like to have my tubes unblocked in order to conceive without IVF treatment. In addition to Wobenzym N, to be precise, what other products should I take along with it and how can I purchase them. More of your advice and suggestions are appreciated. Thank you kindly.

    • Hi Ruth,

      You can learn natural options for uterine fibroids here:

      Learn natural support options for fallopian tube health here:

      Fallopian tubes that are severely damaged need special care. In those cases we would suggest you work with a specialist. A specialist will be able to evaluate your unique situation and determine the best possible course of care. Clear Passage Physical Therapy Clinics are a great option for those who do not want surgery. It is important to recognize that the fallopian tubes are about the size of a spaghetti noodle in width and are very delicate. Any sort of trauma can alter their function and damage the tubal tissues. Once they are damaged it may be difficult to reverse that damage. In that case, only IVF is an option for achieving pregnancy.

  29. Hi
    I am going for an operation to remove scar tissues from my womb. I have ashermans syndrome . When can I start taking this to help prevent /reduce regrowth ?

    • Elizabeth Willett, MA, CH

      Hello Nellie ~ It is best to wait to begin using Systemic Enzyme Therapy until you have healed from surgery. For each person this is different, but in general 2-3 weeks. Wobenzym N, which is the enzyme blend used in this therapy, is not intended for use during times of heavy bleeding (menstruation and otherwise). Best wishes for an easy, quick procedure and speedy healing!

  30. Hi
    I wda diagnosed epidadmes obstruction azopspermia
    Can you help me what remove my obstruction.

  31. Can I make an order of the enzymes and get it delivered to Lagos, Nigeria? I am 30 years, and I have been battling ovarian cysts and endometriosis for a while. I would be getting married in 3 months and 3 weeks and I would prefer to use natural remedies instead of surgery in taking care of this problem and boosting my fertility. How can you help?
    Thank you.

    • Hi Daisy,

      Congratulations on the wedding news! Please contact our customer service regarding shipping options for Nigerians.

      A consultation with one of our herbalists may greatly help you to know what natural therapies are best for your needs. To be honest sometimes surgery is necessary to improve health. The stage of endometriosis you are in will play a huge role in how well the body will respond to natural therapies for these conditions. In advanced cases, it may be best to consider medical options combined with natural therapy options.

  32. dear Hethir
    I ve made up mind to go for sugery again to remove fibroids so that I can have children, at what point do I start taking wobenzym n to prevent scar tissues and adhesions. I have also ordered for the fertility cleanse, castor oil pack and the massage dvd
    Thanking you for your response

    • Hi Nana,

      Systemic Enzyme Therapy using Wobenzym N should be discontinued 2 weeks prior to surgery and not begun again for at least 2 weeks post-operation. It is best to not begin any of the other therapies until you are fully healed from surgery, so 2 weeks to a month post operation. Take it easy, go slow. Sending you blessings for your upcoming procedure.

  33. Do you have a kit for systemic enzyme therapy?

    • We do contain two kits that contain systemic enzyme therapy.

      FallopianWise Kit
      EndoWise Kit
      OvarianWise Kit

      Contact customer service for more information.

    • Hello
      Can I take Wobenzym N and at the same time Adrenal Strength ?

    • Elizabeth Willett, MA, CH

      Hello Andy!

      Yes you can take Wobenzym N with Adrenal Strength. However given Wobenzym N is not to be taken with food and Adrenal Strength is made from food, it may best to take them at separate times in the day.