Clomid: Natural Alternatives to Clomid

Clomid: Natural Alternatives to Clomid

For women facing infertility due to anovulation (lack of ovulation), or irregular ovulation, due to PCOS or other fertility issues, Clomid is often one of the first fertility medications suggested by doctors. Why? This drug is a selective estrogen receptor modulator (SERM). It increases production of gonadotropins (hormones released by the pituitary gland) by inhibiting negative feedback on the hypothalamus. It is used for ovarian hyperstimulation for IVF preparation, and to stimulate and regulate ovulation in women with anovulatory cycles. It is most commonly used for women with PCOS.

To make a long story short- this drug forces the body to ovulate, sometimes stimulating ovulation of multiple follicles.

Clomid is the name for the medication clomifene or clomiphene. Clomid use began in the 1960s and has been used on thousands of women. This long history of use gives us a clear picture of common side effects. The use of Clomid comes with the possibility of the following common side effects:

  • multiple births
  • enlarged ovaries
  • pain and bloating in the abdomen/pelvis
  • headache
  • nausea
  • mid-cycle spotting
  • heavy menstrual bleeding

Other side effects include mood swings, headaches, fatigue, and breast tenderness. In approximately 30% of women taking Clomid, their cervical mucous will become hostile to sperm, thereby preventing conception.

There are many other rare side effects, including possibility of ovarian hyperstimulation syndrome and ovarian rupture. The risk for this goes up with each subsequent round of use.

Natural Alternatives to Clomid

If you are reading this article it is probably because you are considering using Clomid or have used it in the past. It may be that you are preparing to go for IVF. But the main reason you are here is because you want to know if there are natural alternatives to Clomid. After all we are dedicated to bringing you the best information on natural therapies for fertility. We want you to be the most vibrant and healthy person you can be. Sometimes despite our best intentions in life, we still end up going for medical fertility treatments and you know what, that is okay! But before you go down that road, consider the best alternatives to Clomid, ways to naturally bring about ovulation and a regular menstrual cycle.

Before beginning Clomid think about your long-term health. While Clomid may help you get pregnant right away, it does not solve the root of the problem. Have you asked yourself, “Why am I not ovulating?” Fertility Herbs work with the body, to bring about real change long-term. This benefits your fertility health in the long run. The overall goal would be to support the overall health of the body, this will bring about the greatest reproductive health.

Clomid cannot solve poor egg health, PCOS, amenorrhea, ect. It is a once a month stimulation drug, which you must go back for each cycle, in hopes that the stimulation will make you to ovulate. Even before you choose to use Clomid, you will increase your chances of successful conception by preparing the body for pregnancy by following a simple, natural protocol for 3-6 months prior to trying to conceive…

Tribulus (Tribulus terrestris)
Tribulus may normalize ovulation in infertile women when used prior to ovulation. One study performed on 36 women who were not ovulating, showed that that 67% realized normal ovulation after only 2-3 months of consistent use. Tribulus has also been found to be a nourishing tonic for the female reproductive system as a whole, especially concerning the ovaries. Rat studies showed that this herb promotes normal ovarian function and reduction in ovarian cysts. Tribulus has also been found to reduce antisperm antibodies.

Vitex also known as Chaste Tree Berry (Vitex agnus-castus)
The berry of this small tree has been found to help normalize ovulation. Vitex supports hormonal balance in the body by having an effect on the hypothalamic-pituitary-ovarian axis (hormonal feedback loop), correcting the problem at the source. Vitex has been used to reduce Polycystic Ovary Syndrome (PCOS) with great results. This herb takes time to be effective, but works to normalize the entire menstrual cycle, not force ovulation.

Shatavari (Asparagus racemosus)
Shatavari’s main constituents are steroidal-sapponins, suggesting its use as an estrogen regulator, the estrogen modulating in turn may contribute to menstrual cycle regulation. This plant has shown to protect the body from stressors, including stress related infertility issues. It combines well with Tribulus terrestris. Shatavari is a supportive female reproductive health tonic. Supports healthy cervical mucous production.

Maca (Lepidium meyenii)
Maca promotes hormonal balance overall, is nourishing to the endocrine system, which controls hormone function. This herb has been shown safe to combine with all the herbs on this page.

Pregnancy Prep Herbal Blend
This herbal formula is specific for women who want to support their reproductive health, improve timing of ovulation, increase uterine health, promote circulation to the reproductive organs, while normalizing progesterone levels. It contains Tribulus, Vitex, Maca and a variety of other supportive herbs. To learn more about this herbal blend click here…

Can Clomid be Combined With Herbs for Fertility?

No. We do not recommend using any herbs for fertility during a fertility medication cycle. A cycle is about one month, or one menstrual cycle. Even if you are using a fertility medication for only one part of your cycle, we do not suggest using any herbs for fertility during other times in that same cycle. Clomid is usually give for 5 days in the beginning of the cycle to stimulate ovulation. Just because you are not taking it for a full cycle, it is best to not use any herbs for fertility in that same cycle.

Plan ahead. If you are thinking of starting a fertility medication, make your doctor appointment for about a month after weaning yourself off of the herbs you are taking. Continuing a multivitamin, cod liver oil, whey protein powder and spirulina would be fine.

Clomid and IVF

The use of Clomid for IVF as part of ART (artificial reproductive technology) is also a common practice. Let us consider for a moment that IVF is usually an infertile couples last choice. How successful is ART?

According to the Centers for Disease Control’s 2009 report on ART of all couples who have gone through ART, only 37% led to pregnancy. 30% resulted in live birth. This means that of the successful ART pregnancies, 19% did not result in live birth. These statistics are not based per woman, they are calculated per new cycle and do not reflect how many ART cycles a woman may have gone through. Consider this, of the 102,478 ART cycles started in 2009, 30,787 resulted in live births. Again, this is where thoughtful natural fertility planning can help to increase chances of a successful IVF. We want you to have not only successful conception, but a healthy pregnancy and birth. To learn the best ways to prepare for IVF, click here…

5. T/AR T2009


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  1. Hi,
    I would like to know what I can take to ensure that I ovulate mature follicles. I have very regular cycles and the doctor confirmed that I do ovulate but my follicles don’t fully mature. We successfully conceived on our first clomid/IUI cycle but I would like to try naturally this time around. Please advise. Thank you.

  2. iam in Kenya,Mombasa region..where do i get these herbs

  3. How to I get the herbs am in Nigeria

  4. Hi,
    I have small follicles on my ovaries and all ultrasounds are negative for problems or cysts. My periods are very irregular. I have been trying to get pregnant with my husband for one year. My doctor doesn’t think I’m ovulating. What herbs would you suggest for me? I currently take a prenatal, biotin and fish oil daily. Will these interact with any herbs??

    • Elizabeth Willett, MA, CH

      Hi Alysia!
      You can take a prenatal multivitamin, biotin and an omega supplement (fish oil) with herbs. This article details herbs that you might try. We have found that your body better responds to a natural fertility program if you first do a Fertility Cleanse. It may benefit you to learn more about Biphasic Herbal Formulas to support the proper timing of your entire menstrual cycle and hormone balance.
      You may also want to consider a Natural Fertility Consultation if you are still unsure of where to start. Our Natural Fertility Consultations provide you with a personalized written guide and audio recording describing to the best natural therapies, herbs and supplements for your unique fertility issues.
      Be Well!

  5. Dear Dalene,
    this is my second post on your site the first was early in this month, kindly do check that in order to review my history.
    Today i have been to my fertility Dr and she told me the cyst they have removed last november was not endometrosis that was only normal cyst.
    Now she prescribed me to start taking clomid D2-D6 from my next cycle.
    but currently i am taking vitex since 2 months, Maca and evening prime rose i have started this month. if no luck this month i would be taking clomid from my next cycle plus Dr prescribed some blood test also during clomid cycle.
    My QUESTION here to you is during clomid cycle which herbal medicine i should continue and which should stop..!

    • Elizabeth Willett, MA, CH

      Dear Malika,

      I hope you don’t mind that I answer for Dalene as she is currently out of the office and I want to get you an answer sooner than later.
      We do not advise combining herbs that have an effect on hormonal balance with Clomid. You would want to stop taking Vitex, Maca and Evening Primrose Oil when you begin taking Clomid.

      In health~ Liz

  6. I am currently taking Vitex, and this is only the end of my first month. I was wondering if vitex can be taken in combination with Tribulus or Maca. I really would like to try tribulus, but the vitex has helped me feel much better already so I don’t want to stop that.

    • Hi Stephanie,

      Yes, Vitex may be combined with Tribulus and Maca. All three are fine to take at the same time. I am glad to hear you are happy with the way vitex is making you feel in just the first month of use.

      All the best!

  7. Hi ,
    I ‘m 43 year old now . I want to have another baby . What should I do or take?